Observational studyInternational journal of colorectal disease2018
Can the combination of laparoscopy and enhanced recovery improve long-term survival after elective colorectal cancer surgery?
Observational study in International journal of colorectal disease, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.
- Oncologic and long-term outcomes of enhanced recovery after surgery in cancer surgeries - a systematic review.World journal of surgical oncology · 2021Pooled it
- A Nomogram for Prediction of Survival in Patients After Gastrectomy Within Enhanced Recovery After Surgery (ERAS): A Single-Center Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2020Trial
- Repeating of local therapy of distant metastases increases overall survival in patients with synchronous metastasized rectal cancer-a monocentric analysis.International journal of colorectal disease · 2018Trial
- Clinical Risk Management and Postoperative Outcomes After Colorectal Resection: A Retrospective Observational Study.Journal of personalized medicine · 2026Article
- The Impact of Enhanced Recovery on Long-Term Survival in Rectal Cancer.Annals of surgical oncology · 2024Article
- Value of enhanced recovery after surgery in patients undergoing endoscopic retrograde cholangiopancreatography with intravenous anaesthesia for choledocholithiasis: a retrospective observational study.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2023Article
- The effect of the enhanced recovery programme on long-term survival following liver resection for colorectal liver metastases.Langenbeck's archives of surgery · 2023Article
- Compliance with enhanced recovery after surgery predicts long-term outcome after hepatectomy for cholangiocarcinoma.World journal of gastrointestinal surgery · 2023Article
- ERAS® protocol improves survival after radical cystectomy: A single-center cohort study.Medicine · 2022Article
- Laparoscopic Versus Open Re-operations Within 30 Days After Lower Gastrointestinal Tract Surgery: a Retrospective Comparative Study.World journal of surgery · 2021Article
- Enhanced Recovery After Surgery in Patients With Hepatocellular Carcinoma Undergoing Laparoscopic Hepatectomy.Frontiers in surgery · 2021Article
- miR-452-5p and miR-215-5p expression levels in colorectal cancer tissues and their relationship with clinicopathological features.Oncology letters · 2020Article
- Does enhanced recovery improve the survival rates of patients 3 years after undergoing surgery to remove a tumor in the colon?International journal of colorectal disease · 2019Article
- Minimally invasive surgery for stage III colon adenocarcinoma is associated with less delay to initiation of adjuvant systemic therapy and improved survival.Surgical endoscopy · 2019Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimEnhanced recovery after surgery (ERAS) programmes and laparoscopic techniques both provide short-term benefits to patients undergoing colorectal cancer surgery. ERAS protocol compliance may improve long-term survival in those undergoing open colorectal resection but as laparoscopic data has not been reported. Therefore, we aimed to investigate the impact of the combination of laparoscopy and ERAS management on 5-year overall survival.
methodsA dedicated prospectively populated colorectal cancer surgery database was reviewed. Patient inclusion criteria were biopsy-proven colorectal adenocarcinoma, undergoing elective surgery undertaken with curative intent. All patients were managed within an established ERAS programme and routinely followed up for 5 years. Overall survival was measured using the log-rank Kaplan-Meier method at 5 years.
resultsEight hundred fifty-four patients met the inclusion criteria. Four hundred eighty-one (56%) cases were laparoscopic with 98 patients (20%) requiring conversion. There were no differences in patient or tumour demographics between the surgical groups. Median ERAS protocol compliance was 93% (range 53-100%). Five-year overall survival was superior in laparoscopic cases compared with that of converted and open surgery (78 vs 68 vs 70%, respectively, p < 0.007). An open approach (HR 1.55, 95%CI 1.16-2.06, p = 0.002) and delayed hospital discharge (> 7 days, HR 1.5, 95%CI 1.13-1.9, p = 0.003) were the only modifiable risk factors associated with poor survival.
conclusionsThe use of a laparoscopic approach with enhanced recovery after surgery management appears to have long-term survival benefits following colorectal cancer resection.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.