ArticleFrontiers in medicine2017
Neuropsychological Correlates of Pre-Frailty in Neurocognitive Disorders: A Possible Role for Metacognitive Dysfunction and Mood Changes.
Article in Frontiers in medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 26 citations in OpenAlex.
- Impact of physical exercise on memory and learning in healthy older women: a quasi-experimental study.BMC geriatrics · 2025Article
- Editorial: Rising stars in neuropsychology 2021.Frontiers in psychology · 2024Article
- Parkinson's Disease, SARS-CoV-2, and Frailty: Is There a Vicious Cycle Related to Hypovitaminosis D?Brain sciences · 2023Review
- Health factors associated with cognitive frailty in older adults living in the community.Frontiers in aging neuroscience · 2023Article
- Editorial: Insights in neuropsychology 2021.Frontiers in psychology · 2023Article
- Longitudinal Study on Sustained Attention to Response Task (SART): Clustering Approach for Mobility and Cognitive Decline.Geriatrics (Basel, Switzerland) · 2022Article
- Neurophysiological and Brain Structural Markers of Cognitive Frailty Differ from Alzheimer's Disease.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022Article
- Measuring Awareness in People With Dementia: Results of a Systematic Scoping Review.Journal of geriatric psychiatry and neurology · 2021Article
- Editorial: Physical and Cognitive Frailty in the Elderly: An Interdisciplinary Approach.Frontiers in psychology · 2021Article
- Investigating Neuroimaging Correlates of Early Frailty in Patients With Behavioral Variant Frontotemporal Dementia: A MRI and FDG-PET Study.Frontiers in aging neuroscience · 2021Article
- A multidimensional approach to frailty in older people.Ageing research reviews · 2020Review
- A Possible Association Between Executive Dysfunction and Frailty in Patients With Neurocognitive Disorders.Frontiers in psychology · 2020Review
- Clinical and Neuropsychological Correlates of Prefrailty Syndrome.Frontiers in medicine · 2020Article
- Screening for Cognitive Frailty Using Short Cognitive Screening Instruments: Comparison of the Chinese Versions of the MoCA and QFrontiers in psychology · 2020Article
- Cognitive function in Prefrail and frail community-dwelling older adults in China.BMC geriatrics · 2019Article
- Pain Anticipation and Nocebo-Related Responses: A Descriptive Mini-Review of Functional Neuroimaging Studies in Normal Subjects and Precious Hints on Pain Processing in the Context of Neurodegenerative Disorders.Frontiers in pharmacology · 2019Review
- Frailty as the Future Core Business of Public Health: Report of the Activities of the A3 Action Group of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA).International journal of environmental research and public health · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRecent studies have suggested that cognitive functions in patients with neurocognitive disorders have a significant role in the pathogenic mechanisms of frailty. Although pre-frailty is considered an intermediate, preclinical state, epidemiological research has begun to dislodge cognition and frailty into their specific subcomponents to understand the relationship among them. We aim to analyse the possible association between pre-frailty and neuropsychological variables to outline which factors can contribute to minor and major neurocognitive disorders.
methods60 subjects complaining of different cognitive deficits underwent a deep-in-wide frailty and neuropsychological assessment. We conducted three multiple linear regression analyses adjusted for a combination of demographic measures and involving several neuropsychological-behavioural parameters selected by the literature on physical frailty.
resultsWe found a significant association between frailty-as measured by the multidimensional prognostic index (MPI)-and action monitoring and monetary gain (cognitive domain), depression and disinhibition (behavioural domain). Moreover, an association between MPI and impaired awareness for instrumental activities disabilities exists.
conclusionWe propose a novel framework for understanding frailty associated with metacognitive-executive dysfunction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.