Evidence map›Paper›PMID 29188202›Full record

ArticleProstate international2017

Seminal plasma enables selection and monitoring of active surveillance candidates using nuclear magnetic resonance-based metabolomics: A preliminary investigation.

Matthew J Roberts, Renee S Richards, Clement W K Chow, Marion Buck, John Yaxley, Martin F Lavin, Horst Joachim Schirra, Robert A Gardiner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Prostate international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. PeerJ · 2026
    Review
  2. Article
  3. Heliyon · 2024
    Article
  4. Prostate cancer in omics era.Cancer cell international · 2022
    Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Potential of nuclear magnetic resonance metabolomics in the study of prostate cancer.Indian journal of urology : IJU : journal of the Urological Society of India
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Matthew J RobertsSchool of Medicine, The University of Queensland, Brisbane, Australia.
Renee S RichardsCentre for Clinical Research, The University of Queensland, Brisbane, Australia.
Clement W K ChowCentre for Clinical Research, The University of Queensland, Brisbane, Australia.
Marion BuckDepartment of Environmental Health Sciences, University Medical Centre Freiburg, Freiburg, Germany.
John YaxleyDepartment of Urology, Royal Brisbane and Women's Hospital, Brisbane, Australia.
Martin F LavinCentre for Clinical Research, The University of Queensland, Brisbane, Australia.
Horst Joachim SchirraCentre for Advanced Imaging, The University of Queensland, Brisbane, Australia.
Robert A GardinerCentre for Clinical Research, The University of Queensland, Brisbane, Australia.
The University of Queensland · AUEdith Cowan University · AURoyal Brisbane and Women's Hospital · AUUniversity Medical Center Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiagnosis and monitoring of localized prostate cancer requires discovery and validation of noninvasive biomarkers. Nuclear magnetic resonance (NMR)-based metabolomics of seminal plasma reportedly improves diagnostic accuracy, but requires validation in a high-risk clinical cohort. MATERIALS AND

methodsSeminal plasma samples of 151 men being investigated for prostate cancer were analyzed with

resultsSeminal plasma metabolites best predicted low- and intermediate-risk prostate cancer with differences observed between these groups and benign samples. Lipids/lipoproteins dominated spectra of high grade samples with less metabolite contributions. Overall prostate cancer prediction using previously described metabolites was not validated.

conclusionMetabolomics of seminal plasma

Indexed as

BiomarkerMetabolomicsNuclear Magnetic Resonance (NMR)Prostate CancerSeminal Fluid

Identifiers

PMID29188202
PMCPMC5693471
OpenAlexW2604038354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.