Evidence map›Paper›PMID 29188012›Full record

ArticleF1000Research2016

Creating, generating and comparing random network models with NetworkRandomizer.

Gabriele Tosadori, Ivan Bestvina, Fausto Spoto, Carlo Laudanna, Giovanni Scardoni

Abstract read
In one paragraph

Article in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gabriele TosadoriDepartment of Computer Science, University of Verona, Verona, 37134, Italy.
Ivan BestvinaFaculty of Electrical Engineering and Computing, University of Zagreb, Zagreb, 10000, Croatia.
Fausto SpotoDepartment of Computer Science, University of Verona, Verona, 37134, Italy.
Carlo LaudannaDepartment of Medicine, University of Verona, Verona, 37134, Italy.
Giovanni ScardoniCenter for BioMedical Computing, University of Verona, Verona, 37134, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological networks are becoming a fundamental tool for the investigation of high-throughput data in several fields of biology and biotechnology. With the increasing amount of information, network-based models are gaining more and more interest and new techniques are required in order to mine the information and to validate the results. To fill the validation gap we present an app, for the Cytoscape platform, which aims at creating randomised networks and randomising existing, real networks. Since there is a lack of tools that allow performing such operations, our app aims at enabling researchers to exploit different, well known random network models that could be used as a benchmark for validating real, biological datasets. We also propose a novel methodology for creating random weighted networks, i.e. the multiplication algorithm, starting from real, quantitative data. Finally, the app provides a statistical tool that compares real versus randomly computed attributes, in order to validate the numerical findings. In summary, our app aims at creating a standardised methodology for the validation of the results in the context of the Cytoscape platform.

Indexed as

cytoscapenetwork analysisnetwork generationnetwork randomisationrandom networks

Identifiers

PMID29188012
PMCPMC5686481

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.