Evidence map›Paper›PMID 29187863›Full record

ArticleFrontiers in genetics2017

Smooth, an hnRNP-L Homolog, Might Decrease Mitochondrial Metabolism by Post-Transcriptional Regulation of Isocitrate Dehydrogenase (Idh) and Other Metabolic Genes in the Sub-Acute Phase of Traumatic Brain Injury.

Arko Sen, Katherine Gurdziel, Jenney Liu, Wen Qu, Oluwademi O Nuga, Rayanne B Burl, Maik Hüttemann, Roger Pique-Regi, Douglas M Ruden

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Review
  3. TBI and Tau Loss of Function Both Affect Naïve Ethanol Sensitivity inInternational journal of molecular sciences · 2024
    Article
  4. Review
  5. Exploring the Research Focus of RNA-Binding Proteins in Trauma and Burns.Analytical cellular pathology (Amsterdam) · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Drosophila as a model to explore secondary injury cascades after traumatic brain injury.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2021
    Review
  12. Article
  13. Inhibiting Mitochondrial CytochromeFrontiers in physiology · 2021
    Article
  14. Article
  15. Article
  16. Modeling Neurodegenerative Disorders inInternational journal of molecular sciences · 2020
    Review
  17. Article
  18. Frontiers in neurology · 2020
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Arko SenInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI, United States.
Katherine GurdzielC. S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, United States.
Jenney LiuCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, United States.
Wen QuDepartment of Pharmacology, Wayne State University, Detroit, MI, United States.
Oluwademi O NugaDepartment of Pharmacology, Wayne State University, Detroit, MI, United States.
Rayanne B BurlC. S. Mott Center for Human Growth and Development, Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, United States.
Maik HüttemannCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, United States.
Roger Pique-RegiCenter for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, United States.
Douglas M RudenInstitute of Environmental Health Sciences, Wayne State University, Detroit, MI, United States.
Wayne State University · US

Funding

Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
Understanding Breastfeeding Practices Among ECHO Cohort Participants Before and During/After the COVID-19 PandemicUH3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI Charles James Barone, MICHAEL R. ELLIOTT · 2018 to 2026
$24.5M
THE ROLE OF CNS INSULIN AS A MODULATOR OF DIABETIC COMPLICATIONSR25GM058905 · NIGMS · WAYNE STATE UNIVERSITY · PI CHOW, CHRISTINE S, DUNBAR, JOSEPH C · 1999 to 2020
$14.4M
Prenatal Exposures and Child Health Outcomes: A Statewide StudyUG3OD023285 · OD · MICHIGAN STATE UNIVERSITY · PI BARONE, CHARLES JAMES, ELLIOTT, MICHAEL R. · 2016 to 2024
$12.9M
Pilot Project ProgramP30ES020957 · NIEHS · WAYNE STATE UNIVERSITY · PI RUNGE-MORRIS, MELISSA A · 2014 to 2021
$10.1M
QTL AND MICROARRAY MAPPING LEAD SENSITIVITY GENESR01ES012933 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2004 to 2015
$3.4M
Functional Characterization of the Genetic and Environmental Determinants of Complex TraitsR01GM109215 · NIGMS · WAYNE STATE UNIVERSITY · PI Francesca Luca, Roger Pique-Regi · 2014 to 2026
$3.2M
NovaSeq Shared Instrumentation Grant for Wayne State UniversityS10OD025170 · OD · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2018 to 2018
$600k
Effects of Lead on Neuronal Differentiation in Human Embryonic Stem CellsR21ES021983 · NIEHS · WAYNE STATE UNIVERSITY · PI RUDEN, DOUGLAS M · 2012 to 2013
$413k
NCI NIH HHS P30 CA022453NIEHS NIH HHS P30 ES020957NIEHS NIH HHS R01 ES012933NIEHS NIH HHS R21 ES021983NIGMS NIH HHS R01 GM109215NIGMS NIH HHS R25 GM058905NIH HHS S10 OD025170NIH HHS UG3 OD023285NIH HHS UH3 OD023285
6 · The paper itself

Abstract

Traumatic brain injury (TBI) can cause persistent pathological alteration of neurons. This may lead to cognitive dysfunction, depression and increased susceptibility to life threatening diseases, such as epilepsy and Alzheimer's disease. To investigate the underlying genetic and molecular basis of TBI, we subjected

Indexed as

alternative splicinghistone modificationhnRNP-Lintron retentionsmoothtraumatic brain injury

Identifiers

PMID29187863
PMCPMC5694756
OpenAlexW2768150619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.