Evidence map›Paper›PMID 29187580›Full record

ArticlePediatrics2017

Computer-Aided Recognition of Facial Attributes for Fetal Alcohol Spectrum Disorders.

Matthew Valentine, Dustin C J Bihm, Lior Wolf, H Eugene Hoyme, Philip A May, David Buckley, Wendy Kalberg, Omar A Abdul-Rahman

Open access · bronzeAbstract read
In one paragraph

Article in Pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
10.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 61 citations in OpenAlex.

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  15. Ocular measurements in fetal alcohol spectrum disorders.American journal of medical genetics. Part A · 2020
    Article
  16. Article
  17. Observational
  18. Article
  19. Fetal Alcohol Spectrum Disorder: Can We Change the Future?Alcoholism, clinical and experimental research · 2020
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Matthew ValentineDepartment of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi.
Dustin C J BihmDepartment of Pediatrics, University of Mississippi Medical Center, Jackson, Mississippi.
Lior WolfFDNA Inc, Boston, Massachusetts.
H Eugene HoymeSanford Research and School of Medicine, University of South Dakota Sanford, Sioux Falls, South Dakota.
Philip A MayGillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
David BuckleyCenter on Alcoholism, Substance Abuse, and Addictions, The University of New Mexico, Albuquerque, New Mexico; and.
Wendy KalbergCenter on Alcoholism, Substance Abuse, and Addictions, The University of New Mexico, Albuquerque, New Mexico; and.
Omar A Abdul-RahmanDepartment of Genetic Medicine, Munroe-Meyer Institute for Genetics and Rehabilitation, University of Nebraska Medical Center, Omaha, Nebraska omar.abdulrahman@unmc.edu.
University of Mississippi Medical Center · USUniversity of New Mexico · USUniversity of Nebraska Medical Center · USUniversity of North Carolina at Chapel Hill · USUniversity of South Dakota · US

Funding

TRIAL OF FAS PREVENTION IN AMERICAN INDIAN COMMUNITIESR01AA011685 · NIAAA · UNIVERSITY OF NEW MEXICO · PI MAY, PHILIP ALAN · 1998 to 2001
$3.1M
NIAAA NIH HHS R01 AA011685
6 · The paper itself

Abstract

objectivesTo compare the detection of facial attributes by computer-based facial recognition software of 2-D images against standard, manual examination in fetal alcohol spectrum disorders (FASD).

methodsParticipants were gathered from the Fetal Alcohol Syndrome Epidemiology Research database. Standard frontal and oblique photographs of children were obtained during a manual, in-person dysmorphology assessment. Images were submitted for facial analysis conducted by the facial dysmorphology novel analysis technology (an automated system), which assesses ratios of measurements between various facial landmarks to determine the presence of dysmorphic features. Manual blinded dysmorphology assessments were compared with those obtained via the computer-aided system.

resultsAreas under the curve values for individual receiver-operating characteristic curves revealed the computer-aided system (0.88 ± 0.02) to be comparable to the manual method (0.86 ± 0.03) in detecting patients with FASD. Interestingly, cases of alcohol-related neurodevelopmental disorder (ARND) were identified more efficiently by the computer-aided system (0.84 ± 0.07) in comparison to the manual method (0.74 ± 0.04). A facial gestalt analysis of patients with ARND also identified more generalized facial findings compared to the cardinal facial features seen in more severe forms of FASD.

conclusionsWe found there was an increased diagnostic accuracy for ARND via our computer-aided method. As this category has been historically difficult to diagnose, we believe our experiment demonstrates that facial dysmorphology novel analysis technology can potentially improve ARND diagnosis by introducing a standardized metric for recognizing FASD-associated facial anomalies. Earlier recognition of these patients will lead to earlier intervention with improved patient outcomes.

Indexed as

Biometric IdentificationChildChild, PreschoolComputersDatabases, FactualFaceFemaleFetal Alcohol Spectrum DisordersHumansMaleROC Curve

Identifiers

PMID29187580
PMCPMC5703776
OpenAlexW2770407030

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.