Evidence map›Paper›PMID 29187553›Full record

ArticleJournal of neurophysiology2018

I

Enrique H S Toloza, Ehsan Negahbani, Flavio Fröhlich

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurophysiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
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  8. Effects ofJournal of neurophysiology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Enrique H S TolozaDepartment of Psychiatry, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
Ehsan NegahbaniDepartment of Cell Biology and Physiology, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
Flavio FröhlichDepartment of Psychiatry, University of North Carolina at Chapel Hill , Chapel Hill, North Carolina.
University of North Carolina at Chapel Hill · US

Funding

Rational Optimization of tACS for Targeting Thalamo-Cortical OscillationsR01MH111889 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FROHLICH, FLAVIO · 2016 to 2019
$2.4M
Targeting Cortical Dynamics: Rational Design of Individualized Brain StimulationR01MH101547 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FROHLICH, FLAVIO · 2013 to 2017
$2.2M
NIMH NIH HHS R01 MH101547NIMH NIH HHS R01 MH111889
6 · The paper itself

Abstract

Transcranial current stimulation (tCS) modulates brain dynamics using weak electric fields. Given the pathological changes in brain network oscillations in neurological and psychiatric illnesses, using alternating electric field waveforms that engage rhythmic activity has been proposed as a targeted, network-level treatment approach. Previous studies have investigated the effects of electric fields at the neuronal level. However, the biophysical basis of the cellular response to electric fields has remained limited. Here, we characterized the frequency-dependent response of different compartments in a layer V pyramidal neuron to exogenous electric fields to dissect the relative contributions of voltage-gated ion channels and neuronal morphology. Hyperpolarization-activated cation current (I

Indexed as

Electric StimulationElectromagnetic FieldsMembrane PotentialsAnimalsDendritesHumansHyperpolarization-Activated Cyclic Nucleotide-Gated ChannelsModels, NeurologicalPyramidal CellsHyperpolarization-Activated Cyclic Nucleotide-Gated Channelsapical dendriteshyperpolarization-activated cation currentlayer 5 pyramidal neuronssubthreshold resonancetranscranial electric field stimulation

Identifiers

PMID29187553
PMCPMC5899309
OpenAlexW2768096625

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.