ArticleProceedings of the National Academy of Sciences of the United States of America2017
SCWISh network is essential for survival under mechanical pressure.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- 3D confinement physically regulates cell cycle progression in budding yeast.Nature communications · 2026Article
- Bacterial growth under confinement requires transcriptional adaptation to resist turgor pressure build-up.Nature communications · 2026Article
- Insight into the role of Sho1 in high-hydrostatic pressure and oxidative stress adaptation of the hadal fungusApplied and environmental microbiology · 2026Article
- The interplay between circadian rhythms and aging: molecular mechanisms and therapeutic strategies.Biogerontology · 2025Review
- Conserved signaling modules regulate filamentous growth in fungi: a model for eukaryotic cell differentiation.Genetics · 2024Review
- Intracellular dry mass density increases under growth-induced pressure.Open research Europe · 2024Article
- Transducing compressive forces into cellular outputs in cancer and beyond.Life science alliance · 2023Review
- Macromolecular crowding limits growth under pressure.Nature physics · 2022Article
- Slipstreaming Mother Machine: A Microfluidic Device for Single-Cell Dynamic Imaging of Yeast.Micromachines · 2020Article
- Mechanical force-induced morphology changes in a human fungal pathogen.BMC biology · 2020Article
- Crosstalk and spatiotemporal regulation between stress-induced MAP kinase pathways and pheromone signaling in budding yeast.Cell cycle (Georgetown, Tex.) · 2020Review
- Mechanical stress impairs pheromone signaling via Pkc1-mediated regulation of the MAPK scaffold Ste5.The Journal of cell biology · 2019Article
- Constricted migration increases DNA damage and independently represses cell cycle.Molecular biology of the cell · 2018Article
- Protein kinase C and calcineurin cooperatively mediate cell survival under compressive mechanical stress.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
Cells that proliferate within a confined environment build up mechanical compressive stress. For example, mechanical pressure emerges in the naturally space-limited tumor environment. However, little is known about how cells sense and respond to mechanical compression. We developed microfluidic bioreactors to enable the investigation of the effects of compressive stress on the growth of the genetically tractable model organism
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.