Evidence map›Paper›PMID 29187382›Full record

ArticleAmerican journal of physiology. Regulatory, integrative and comparative physiology2018

Opposing effects of bronchopulmonary C-fiber subtypes on cough in guinea pigs.

Yang-Ling Chou, Nanako Mori, Brendan J Canning

Open access · greenAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Regulatory, integrative and comparative physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 50 citations in OpenAlex.

  1. Review
  2. Review
  3. Nitric oxide synthase activation in nTS is essential to NMDA receptor dependent encoding of the cough reflex.American journal of physiology. Regulatory, integrative and comparative physiology · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Identifying vagal bronchopulmonary afferents mediating cough response to inhaled sulfur dioxide in mice.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  11. Article
  12. Infectious and Inflammatory Pathways to Cough.Annual review of physiology · 2023
    Review
  13. Article
  14. Review
  15. Cough hypersensitivity and chronic cough.Nature reviews. Disease primers · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yang-Ling ChouJohns Hopkins Asthma and Allergy Center , Baltimore, Maryland.
Nanako MoriJohns Hopkins Asthma and Allergy Center , Baltimore, Maryland.
Brendan J CanningJohns Hopkins Asthma and Allergy Center , Baltimore, Maryland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have addressed the hypothesis that the opposing effects of bronchopulmonary C-fiber activation on cough are attributable to the activation of C-fiber subtypes. Coughing was evoked in anesthetized guinea pigs by citric acid (0.001-2 M) applied topically in 100-µl aliquots to the tracheal mucosa. In control preparations, citric acid evoked 10 ± 1 coughs cumulatively. Selective activation of the pulmonary C fibers arising from the nodose ganglia with either aerosols or continuous intravenous infusion of adenosine or the 5-HT

Indexed as

Action PotentialsAdenosineAnimalsBradykininCitric AcidCoughDisease Models, AnimalGuinea PigsHistamineMaleNerve Fibers, UnmyelinatedNodose GanglionPurinergic P1 Receptor AgonistsReflexRespiratory RateSerotonin2-methyl-5-HTAdenosineBradykininCitric AcidHistaminePurinergic P1 Receptor AgonistsSerotoninSerotonin 5-HT3 Receptor Agonistsadenosinebradykinincapsaicinjugularnodoseserotonin

Identifiers

PMID29187382
PMCPMC5899253
OpenAlexW2768511379

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.