ArticleBlood2018
Nbeal2 interacts with Dock7, Sec16a, and Vac14.
Open access · bronzeAbstract read
In one paragraph
Article in Blood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 41 citations in OpenAlex.
- Environmental benzene exposure induces a conserved neutrophil degranulation program across species.Toxicological sciences : an official journal of the Society of Toxicology · 2026Article
- Nbeal2 Inactivation Triggers Abl1 Stabilisation and Dysregulated Subcellular Localisation of the Multi-Drug-Resistant Protein MDR1 (ABCB1) in Mast Cells.Immunology · 2026Article
- The winding road to platelet α-granules.Frontiers in cell and developmental biology · 2025Review
- Neurobeachin regulates hematopoietic progenitor differentiation and survival by modulating Notch activity.Blood advances · 2024Article
- Article
- NBEAL2 deficiency in humans leads to low CTLA-4 expression in activated conventional T cells.Nature communications · 2023Article
- Article
- COMManding platelet α-granule cargo.Blood · 2022Article
- Pathogenic alleles in microtubule, secretory granule and extracellular matrix-related genes in familial keratoconus.Human molecular genetics · 2021Article
- Thrombocytopathies: Not Just Aggregation Defects-The Clinical Relevance of Procoagulant Platelets.Journal of clinical medicine · 2021Review
- Neutrophil specific granule and NETosis defects in gray platelet syndrome.Blood advances · 2021Article
- A Deep Dive into the Pathology of Gray Platelet Syndrome: New Insights on Immune Dysregulation.Journal of blood medicine · 2021Review
- Insights into Lysosomal PI(3,5)PMolecular cell · 2020Article
- Novel manifestations of immune dysregulation and granule defects in gray platelet syndrome.Blood · 2020Article
- Molecular mechanisms of bleeding disorderassociated GFI1BHaematologica · 2019Article
- The road to lysosome-related organelles: Insights from Hermansky-Pudlak syndrome and other rare diseases.Traffic (Copenhagen, Denmark) · 2019Review
- Nbeal2 Deficiency Increases Organ Damage but Does Not Affect Host Defense During Gram-Negative Pneumonia-Derived Sepsis.Arteriosclerosis, thrombosis, and vascular biology · 2018Article
Corrections and comments
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Authors and funding
18 authors at 8 institutions in 2 countries.
Louisa MayerDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Maria JasztalDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Mercedes PardoWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Salvadora Aguera de HaroDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Janine CollinsDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Tadbir K BarianaDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Peter A SmethurstDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Luigi GrassiDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Romina PetersenDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Paquita NurdenInstitut Hospitalo-Universitaire L'Institut de Rythmologie et Modelisation Cardiaque, Hopital Xavier Arnozan, Pessac, France.
Rémi FavierDépartement d'Hématologie, Assistance-Publique Hôpitaux de Paris, Centre de Référence des Pathologies Plaquettaires, Hôpital Armand Trousseau, Paris, France.
Lu YuWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Stuart MeachamDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
William J AstleCardiovascular Epidemiology Unit of the Medical Research Council/British Heart Foundation, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom; and.
Jyoti ChoudharyWellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom.
Wyatt W YueStructural Genomics Consortium, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom.
Willem H OuwehandDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
Jose A GuerreroDepartment of Haematology, University of Cambridge, Cambridge, United Kingdom.
University of Cambridge · GBNational Health Service · GBWellcome Sanger Institute · GBElectrophysiology and Heart Modeling Institute · FRInserm · FRMedical Research Council · GBRoyal Free London NHS Foundation Trust · GBUniversity of Oxford · GB
Funding
British Heart Foundation RG/13/13/30194Medical Research Council MR/L003120/1Medical Research Council MR/P02002X/1Medical Research Council WT098503
Abstract
Mutations in
Indexed as
AnimalsBlood PlateletsBlood ProteinsGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsHEK293 CellsHumansIntracellular Signaling Peptides and ProteinsMegakaryocytesMembrane ProteinsMiceMice, KnockoutMutationProtein BindingVesicular Transport ProteinsBlood ProteinsDOCK7 protein, humanDock7 protein, mouseGTPase-Activating ProteinsGuanine Nucleotide Exchange FactorsIntracellular Signaling Peptides and ProteinsMembrane ProteinsNBEAL2 protein, humanNbeal2 protein, mouseSEC16A protein, humanSec16a protein, mouseVAC14 protein, humanVac14 protein, mouseVesicular Transport Proteins
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.