Evidence map›Paper›PMID 29187364›Full record

ArticleAmerican journal of physiology. Cell physiology2018

Characterization of CD38 in the major cell types of the heart: endothelial cells highly express CD38 with activation by hypoxia-reoxygenation triggering NAD(P)H depletion.

James Boslett, Craig Hemann, Fedias L Christofi, Jay L Zweier

Open access · greenAbstract readComparative Study
In one paragraph

Article in American journal of physiology. Cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. CD38 connects the heart and brain.Translational psychiatry · 2025
    Review
  6. CD38bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. The Role of Inflammation in Age-Associated Changes in Red Blood System.International journal of molecular sciences · 2023
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

James BoslettDepartment of Internal Medicine, Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University , Columbus, Ohio.
Craig HemannDepartment of Internal Medicine, Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University , Columbus, Ohio.
Fedias L ChristofiDepartment of Anesthesiology, Wexner Medical Center at Ohio State University, Columbus, Ohio.
Jay L ZweierDepartment of Internal Medicine, Davis Heart and Lung Research Institute, College of Medicine, The Ohio State University , Columbus, Ohio.
The Ohio State University · USThe Ohio State University Wexner Medical Center · US

Funding

Role of Cytoglobin in the Regulation of Vascular ToneR01HL131941 · NHLBI · OHIO STATE UNIVERSITY · PI JAY Louis ZWEIER · 2017 to 2026
$5.7M
Mechanisms of Nicotine Inhalation-Induced Cardiovascular DiseaseR01HL135648 · NHLBI · OHIO STATE UNIVERSITY · PI ZWEIER, JAY LOUIS · 2017 to 2021
$2.6M
Human enteric glia: A novel target for motility and postoperative ileusR01DK113943 · NIDDK · OHIO STATE UNIVERSITY · PI CHRISTOFI, FEDIAS LEONTIOU, GRIDER, JOHN R · 2017 to 2019
$1.4M
NHLBI NIH HHS R01 HL131941NHLBI NIH HHS R01 HL135648NIDDK NIH HHS R01 DK113943
6 · The paper itself

Abstract

The NAD(P)

Indexed as

ADP-ribosyl CyclaseADP-ribosyl Cyclase 1AnimalsCell HypoxiaCoronary VesselsEndothelial CellsEnzyme ActivationFibroblastsMembrane GlycoproteinsMice, Inbred C57BLMice, KnockoutMyocardial ReperfusionMyocardial Reperfusion InjuryMyocytes, CardiacNADPNitric OxideADP-ribosyl CyclaseADP-ribosyl Cyclase 1Cd38 protein, mouseCd38 protein, ratMembrane GlycoproteinsNADPNitric OxideNitric Oxide Synthase Type IIINos3 protein, mouseNos3 protein, ratSuperoxidesendotheliumeNOSischemia-reperfusionNAD(P)(H)nitric oxidesuperoxide

Identifiers

PMID29187364
PMCPMC6335017
OpenAlexW2769944289

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.