Evidence map›Paper›PMID 29187167›Full record

ArticleBMC ophthalmology2017

High ocular CMV copies and mismatched receipts may predict poor visual prognosis in CMV retinitis patients following allogeneic haematopoietic stem cell transplantation.

Yuehong Zhang, Xiangcai Ruan, Weizhong Yang, Ling Li, Zhuanhua Xian, Qiting Feng, Wenjian Mo

Open access · goldAbstract read
In one paragraph

Article in BMC ophthalmology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Yuehong ZhangDepartment of Ophthalmology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510080, China.
Xiangcai RuanDepartments of Anesthesia and Pain Medicine, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510080, China.
Weizhong YangDepartment of Ophthalmology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510080, China.
Ling LiDepartment of Medical Information, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510080, China.
Zhuanhua XianDepartment of Ophthalmology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510080, China.
Qiting FengDepartment of Ophthalmology, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, 510080, China.
Wenjian MoDepartment of Hematology, Guangzhou First People's Hospital, Guangzhou Medical University, No.1 Panfu Road, Yuexiu District, Guangzhou, 510080, China. wenjianmo@163.com.
Guangzhou Medical University · CNGuangzhou First People's Hospital · CNFirst Affiliated Hospital of Guangzhou Medical University · CN

Funding

Guangdong Science and Technology Project 2014A020212521
6 · The paper itself

Abstract

backgroundTo summarize the clinical characteristics and potential factors affecting the visual outcomes in patients with cytomegalovirus retinitis following allogeneic haematopoietic stem cell transplantation (HSCT).

methodsThis retrospective study enrolled 12 patients (19 eyes) with cytomegalovirus retinitis after HSCT at Guangzhou First People's Hospital in China between January 2013 and December 2014. Demographic and clinical characteristics, ocular manifestations and visual outcomes were evaluated by reviewing medical records at the Departments of Hematology and Ophthalmology. All patients were followed up at least 6 months after stopping antiviral therapy. The visual outcome was defined as improvement, stabilization and deterioration.

resultsThe subjects were composed of 7 human leucocyte antigen-matched and 5 mismatched receipts. All patients received combined systemic and intravitreous antiviral therapy. Eleven eyes gained improved or stabilized visual acuity, while 8 eyes suffered deterioration. Eyes with cytomegalovirus load less than 1 × 10

conclusionsHigh ocular cytomegalovirus copies and mismatched receipts may be potential adverse factors affecting visual outcomes in cytomegalovirus retinitis patients following allogeneic HSCT.

Indexed as

Hematopoietic Stem Cell TransplantationAdolescentAdultAntiviral AgentsCytomegalovirus RetinitisFemaleHLA AntigensHumansMaleMiddle AgedPrognosisRetrospective StudiesTissue DonorsVisual AcuityVitreous BodyYoung AdultAntiviral AgentsHLA AntigensInfectionRetinaVision

Identifiers

PMID29187167
PMCPMC5707780
OpenAlexW2771046188

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.