SynthesisBMC nephrology2017
Nephrolithiasis and risk of hypertension: a meta-analysis of observational studies.
Synthesis in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 52 citations in OpenAlex.
- Causal effects of modifiable risk factors on kidney stones: a bidirectional mendelian randomization study.BMC medical genomics · 2023Pooled it
- Association between metabolic syndrome components and the risk of developing nephrolithiasis: A systematic review and bayesian meta-analysis.F1000Research · 2021Pooled it
- ABO blood group distribution in patients with upper urinary tract stones: a case-control study.Urolithiasis · 2026Article
- Identification of cardiovascular disease in patients with kidney stone disease using explainable machine learning.Frontiers in cardiovascular medicine · 2026Article
- Development and validation of a machine learning-based prediction model for urinary calculi recurrence.Urolithiasis · 2025Article
- Hydrochlorothiazide and Bone Mineral Density in Patients with Kidney Stones: Post Hoc Analysis of the NOSTONE Trial.Clinical journal of the American Society of Nephrology : CJASN · 2025Article
- Kidney failure from kidney stones: an ANZDATA study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Article
- Single-Cell RNA Sequencing Analysis Reveals the Role of Macrophage-Mediated CD44-AKT-CCL2 Pathways in Renal Tubule Injury during Calcium Oxalate Crystal Formation.Research (Washington, D.C.) · 2025Article
- Association between triglyceride-glucose index and risk of kidney stone: a Chinese population-based case-control study.BMJ open · 2024Article
- Article
- Association between novel anthropometric indices and prevalence of kidney stones in US adults.World journal of urology · 2023Article
- Oxalate (dys)Metabolism: Person-to-Person Variability, Kidney and Cardiometabolic Toxicity.Genes · 2023Review
- Hospitalization Burden of Patients with Kidney Stones and Metabolic Comorbidities in Spain during the Period 2017-2020.Metabolites · 2023Article
- A nomogram for predicting the risk of residual stone fragments after ureteroscopy.Translational andrology and urology · 2023Article
- Pediatric Nephrolithiasis.Healthcare (Basel, Switzerland) · 2023Review
- Association between N, N-diethyl-m-toluamide exposure and the odds of kidney stones in US adults: a population-based study.Frontiers in public health · 2023Article
- Nephrolithiasis: A Red Flag for Cardiovascular Risk.Journal of clinical medicine · 2022Review
- Cystinuria: An Overview of Diagnosis and Medical Management.Turkish archives of pediatrics · 2022Article
- Endothelial Dysfunction: An Intermediate Clinical Feature between Urolithiasis and Cardiovascular Diseases.International journal of molecular sciences · 2022Review
- An empirical study on hospital-based prevention of recurrent urinary stone disease in Germany.World journal of urology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObservational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence.
methodsPubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were searched to identify observational studies that reported study-specific risk estimates comparing the risk of hypertension in patients with nephrolithiasis. We used a random-effect model to pool the study-specific risk estimates. We also assessed the potential heterogeneity by subgroup analyses, meta-regression analyses, and sensitivity analyses.
resultsA total of 7 articles including 9 studies (n = 313,222 participants) were eventually identified in this meta-analysis. In comparison with the patients who did not have nephrolithiasis, nephrolithiasis significantly increased the risk of hypertension (OR, 1.43; 95% CI, 1.30-1.56), with significant heterogeneity between these studies (I
conclusionsNephrolithiasis is associated with increased risk of hypertension. Future randomized, high-quality clinical trials are encouraged to definitively clarify the relationship between nephrolithiasis and hypertension, which may influence clinical management and primary prevention of hypertension in nephrolithiasis patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.