Evidence map›Paper›PMID 29186951›Full record

ArticleJournal of agricultural and food chemistry2018

Exposure Assessment of Acetamide in Milk, Beef, and Coffee Using Xanthydrol Derivatization and Gas Chromatography/Mass Spectrometry.

Ramin Vismeh, Diane Haddad, Janette Moore, Chandra Nielson, Bryan Bals, Tim Campbell, Allen Julian, Farzaneh Teymouri, A Daniel Jones, Venkataraman Bringi

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Journal of agricultural and food chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Ramin VismehMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
Diane HaddadMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
Janette MooreMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
Chandra NielsonMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
Bryan BalsMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
Tim CampbellMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
Allen JulianMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
Farzaneh TeymouriMichigan Biotechnology Institute , Lansing, Michigan 48910, United States.
A Daniel JonesDepartment of Biochemistry and Molecular Biology, Michigan State University , East Lansing, Michigan 48824, United States.ORCID http://orcid.org/0000-0002-7408-6690
Venkataraman BringiDepartment of Chemical Engineering and Materials Science, Michigan State University , East Lansing, Michigan 48824, United States.
Biotechnology Institute · USMichigan State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acetamide has been classified as a possible human carcinogen, but uncertainties exist about its levels in foods. This report presents evidence that thermal decomposition of N-acetylated sugars and amino acids in heated gas chromatograph injectors contributes to artifactual acetamide in milk and beef. An alternative gas chromatography/mass spectrometry protocol based on derivatization of acetamide with 9-xanthydrol was optimized and shown to be free of artifactual acetamide formation. The protocol was validated using a surrogate analyte approach based on d

Indexed as

AcetamidesAnimalsCattleCoffeeFood ContaminationGas Chromatography-Mass SpectrometryMeatMilkXanthenesacetamideAcetamidesCoffeeXanthenesxanthydrolacetamideanalytical artifactsfood safetymethod validationN-acetylated sugarssurrogate analyte validationthermal degradation

Identifiers

PMID29186951
PMCPMC5765534
OpenAlexW2774506794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.