ReviewLife (Basel, Switzerland)2017
Ecology and Evolution in the RNA World Dynamics and Stability of Prebiotic Replicator Systems.
Review in Life (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Parasites constrain within-population diversification while accelerating between-population divergence in an RNA replication system.Molecular biology and evolution · 2026Article
- The ecology and evolution of sub-exponential replicators.PLoS computational biology · 2026Article
- Thermodynamics of Darwinian selection in molecular replicators.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Article
- The dynamics of prebiotic take-off: the transfer of functional RNA communities from mineral surfaces to vesicles.Communications biology · 2025Article
- Group-selection via aggregative propagule-formation enables cooperative multicellularity in an individual based, spatial model.PLoS computational biology · 2024Article
- Article
- A Proposal of the Ur-RNAome.Genes · 2023Article
- RNA World Modeling: A Comparison of Two Complementary Approaches.Entropy (Basel, Switzerland) · 2022Article
- Hitting Times of Some Critical Events in RNA Origins of Life.Life (Basel, Switzerland) · 2021Article
- Novelty and imitation within the brain: a Darwinian neurodynamic approach to combinatorial problems.Scientific reports · 2021Article
- Article
- Catalytic promiscuity in the RNA World may have aided the evolution of prebiotic metabolism.PLoS computational biology · 2021Article
- Evolution of linkage and genome expansion in protocells: The origin of chromosomes.PLoS genetics · 2020Article
- Dynamics and stability in prebiotic information integration: an RNA World model from first principles.Scientific reports · 2020Article
- Article
- Multilevel selection as Bayesian inference, major transitions in individuality as structure learning.Royal Society open science · 2019Article
- Low-Digit and High-Digit Polymers in the Origin of Life.Life (Basel, Switzerland) · 2019Article
- The Beginning of Systems Chemistry.Life (Basel, Switzerland) · 2019Review
- Stable coevolutionary regimes for genetic parasites and their hosts: you must differ to coevolve.Biology direct · 2018Article
- Mathematical modeling reveals spontaneous emergence of self-replication in chemical reaction systems.The Journal of biological chemistry · 2018Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As of today, the most credible scientific paradigm pertaining to the origin of life on Earth is undoubtedly the RNA World scenario. It is built on the assumption that catalytically active replicators (most probably RNA-like macromolecules) may have been responsible for booting up life almost four billion years ago. The many different incarnations of nucleotide sequence (string) replicator models proposed recently are all attempts to explain on this basis how the genetic information transfer and the functional diversity of prebiotic replicator systems may have emerged, persisted and evolved into the first living cell. We have postulated three necessary conditions for an RNA World model system to be a dynamically feasible representation of prebiotic chemical evolution: (1) it must maintain and transfer a sufficient diversity of information reliably and indefinitely, (2) it must be ecologically stable and (3) it must be evolutionarily stable. In this review, we discuss the best-known prebiotic scenarios and the corresponding models of string-replicator dynamics and assess them against these criteria. We suggest that the most popular of prebiotic replicator systems, the hypercycle, is probably the worst performer in almost all of these respects, whereas a few other model concepts (parabolic replicator, open chaotic flows, stochastic corrector, metabolically coupled replicator system) are promising candidates for development into coherent models that may become experimentally accessible in the future.
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