Evidence map›Paper›PMID 29186863›Full record

ReviewInternational journal of molecular sciences2017

Paraneoplastic Pemphigus: Insight into the Autoimmune Pathogenesis, Clinical Features and Therapy.

Giovanni Paolino, Dario Didona, Giuseppe Magliulo, Giannicola Iannella, Biagio Didona, Santo Raffaele Mercuri, Elisa Moliterni, Michele Donati, Andrea Ciofalo, Guido Granata and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it, 135 citations in OpenAlex.

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1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Giovanni PaolinoUnit of Dermatology and Cosmetology, IRCCS University Vita-Salute San Raffaele, 20132 Milan, Italy. paolgio@libero.it.
Dario DidonaPrima Divisione di Dermatologia, Istituto Dermopatico dell'Immacolata-IRCCS, Via dei Monti di Creta, 104, 00167 Roma, Italy. dario.didona@gmail.com.
Giuseppe MagliuloDipartimento di Organi di Senso, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. giuseppe.magliulo@uniroma1.it.
Giannicola IannellaDipartimento di Organi di Senso, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. giannicola.iannella@uniroma1.it.ORCID 0000-0003-1781-2809
Biagio DidonaPrima Divisione di Dermatologia, Istituto Dermopatico dell'Immacolata-IRCCS, Via dei Monti di Creta, 104, 00167 Roma, Italy. b.didona@idi.it.
Santo Raffaele MercuriUnit of Dermatology and Cosmetology, IRCCS University Vita-Salute San Raffaele, 20132 Milan, Italy. mercuri.santoraffaele@hsr.it.
Elisa MoliterniDipartimento di Medicina Interna e Specialità Mediche, Dermatologia, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. elisa.moliterni@gmail.com.
Michele DonatiDipartimento di Anatomia Patologica, Università Campus-Biomedico, 00128 Roma, Italy. micheledonati25@gmail.com.
Andrea CiofaloDipartimento di Organi di Senso, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. andrea.ciofalo@uniroma1.it.
Guido GranataDipartimento di Immunologia Clinica, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. guido.granata@uniroma1.it.
Patricia RanuzziDipartimento di Farmacologia, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. patricia.ranuzzi@alice.it.
Vincenzo FalascaDipartimento di Organi di Senso, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. vincenzo.falasca@uniroma1.it.
Stefano CalvieriDipartimento di Medicina Interna e Specialità Mediche, Dermatologia, Sapienza Università di Roma, Piazzale Aldo Moro, 5, 00185 Roma, Italy. stefano.calvieri@uniroma1.it.
Sapienza University of Rome · ITIstituto Dermopatico dell'Immacolata · ITVita-Salute San Raffaele University · ITUniversità Campus Bio-Medico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients. The pathogenesis of paraneoplastic pemphigus is not yet completely understood, although some immunological aspects have been recently clarified. Because of its rarity, several diagnostic criteria have been proposed. Besides, several diagnostic procedures have been used for the diagnosis, including indirect immunofluorescence, direct immunofluorescence, and ELISA. We reviewed the most recent literature, searching on PubMed "paraneoplastic pemphigus". We included also papers in French, German, and Spanish. We found 613 papers for "paraneoplastic pemphigus". Among them, 169 were review papers. Because of its varying clinical features, paraneoplastic pemphigus still represents a challenge for clinicians. Furthermore, diagnosis and management of paraneoplastic pemphigus requires close collaboration between physicians, including dermatologist, oncologist, and otorhinolaryngologist.

Indexed as

Diagnosis, DifferentialHumansImmunologic FactorsParaneoplastic SyndromesPemphigusImmunologic Factorsoncologyoral lesionsparaneoplastic pemphigustherapy

Identifiers

PMID29186863
PMCPMC5751135
OpenAlexW2771019980

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.