Evidence map›Paper›PMID 29186770›Full record

ArticleInternational journal of molecular sciences2017

The Evaluation of Pro-Cognitive and Antiamnestic Properties of Berberine and Magnoflorine Isolated from Barberry Species by Centrifugal Partition Chromatography (CPC), in Relation to QSAR Modelling.

Wirginia Kukula-Koch, Marta Kruk-Słomka, Katarzyna Stępnik, Radosław Szalak, Grażyna Biała

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Emodin-8-Molecules (Basel, Switzerland) · 2023
    Article
  5. Magnoflorine fromInternational journal of molecular sciences · 2023
    Article
  6. Article
  7. Isoquinoline Alkaloids fromInternational journal of molecular sciences · 2022
    Article
  8. Article
  9. Article
  10. Article
  11. Bio-Guided Fractionation of Stem Bark Extracts fromMolecules (Basel, Switzerland) · 2021
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. A critical review: traditional uses, phytochemistry, pharmacology and toxicology ofPhytochemistry reviews : proceedings of the Phytochemical Society of Europe · 2020
    Review
  18. Review
  19. Basic and clinical neuroscience
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Wirginia Kukula-KochChair and Department of Pharmacognosy with Medicinal Plant Unit, Medical University in Lublin, 20-093 Lublin, Poland
Marta Kruk-SłomkaDepartment of Pharmacology and Pharmacodynamics, Medical University of Lublin, 20-093 Lublin, Poland
Katarzyna StępnikFaculty of Chemistry, Chair of Physical Chemistry, Department of Planar Chromatography, Maria Curie-Skłodowska University, 20-031 Lublin, Poland
Radosław SzalakDepartment of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Science, 20-950 Lublin, Poland
Grażyna BiałaDepartment of Pharmacology and Pharmacodynamics, Medical University of Lublin, 20-093 Lublin, Poland
Medical University of Lublin · PLMaria Curie-Skłodowska University · PLUniversity of Life Sciences in Lublin · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Civilization diseases associated with memory disorders are important health problems occurring due to a prolonged life span. The manuscript shows the results of an in vivo study targeting the emergence of two drug candidates with anti-amnestic properties. The preceding quantitative structure-activity relationship (QSAR) studies provided information on the ability of berberine and magnoflorine to cross the blood-brain barrier (BBB). In the light of these findings, both compounds were purified from crude plant extracts of barberries: berberine-from

Indexed as

AmnesiaAnimalsAporphinesBerberineBerberisCognitionMaleMemoryMiceQuantitative Structure-Activity RelationshipAporphinesBerberinemagnoflorinealkaloidsBerberiscounter-current chromatographymemory and learningmicepassive avoidance test

Identifiers

PMID29186770
PMCPMC5751114
OpenAlexW2770020522

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.