ArticlePlant & cell physiology2018
The Intracellular Localization of the Vanillin Biosynthetic Machinery in Pods of Vanilla planifolia.
Article in Plant & cell physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 60 citations in OpenAlex.
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- Comparative transcriptome profiling of vanilla (Vanilla planifolia) capsule development provides insights of vanillin biosynthesis.BMC plant biology · 2025Article
- Navigating the challenges of engineering composite specialized metabolite pathways in plants.The Plant journal : for cell and molecular biology · 2025Review
- Genetic Engineering Approaches for the Microbial Production of Vanillin.Biomolecules · 2024Review
- Gamma Irradiation Promotes the Growth Rate of Thai Pigmented Rice As Well As Inducing the Accumulation of Bioactive Compounds and Carbohydrate Hydrolyzing Enzymes Inhibitors (α-Glucosidase and α-Amylase) under Salt Conditions.Preventive nutrition and food science · 2023Article
- Is a spice missing from the recipe? The intra-cellular localization of vanillin biosynthesis needs further investigations.Plant biology (Stuttgart, Germany) · 2023Article
- Reconstitution of monoterpene indole alkaloid biosynthesis in genome engineered Nicotiana benthamiana.Communications biology · 2022Article
- A whiff of the future: functions of phenylalanine-derived aroma compounds and advances in their industrial production.Plant biotechnology journal · 2022Review
- Developing efficient vanillin biosynthesis system by regulating feruloyl-CoA synthetase and enoyl-CoA hydratase enzymes.Applied microbiology and biotechnology · 2022Article
- Anthocyanic Vacuolar Inclusions: From Biosynthesis to Storage and Possible Applications.Frontiers in chemistry · 2022Review
- A phased Vanilla planifolia genome enables genetic improvement of flavour and production.Nature food · 2020Article
- Characterization of the UDP-glycosyltransferase UGT72 Family in Poplar and Identification of Genes Involved in the Glycosylation of Monolignols.International journal of molecular sciences · 2020Article
- Application of Mass Spectrometry Imaging for Visualizing Food Components.Foods (Basel, Switzerland) · 2020Review
- To flourish or perish: evolutionary TRiPs into the sensory biology of plant-herbivore interactions.Pflugers Archiv : European journal of physiology · 2019Review
- Dynamic metabolic solutions to the sessile life style of plants.Natural product reports · 2018Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vanillin is the most important flavor compound in the vanilla pod. Vanilla planifolia vanillin synthase (VpVAN) catalyzes the conversion of ferulic acid and ferulic acid glucoside into vanillin and vanillin glucoside, respectively. Desorption electrospray ionization mass spectrometry imaging (DESI-MSI) of vanilla pod sections demonstrates that vanillin glucoside is preferentially localized within the mesocarp and placental laminae whereas vanillin is preferentially localized within the mesocarp. VpVAN is present as the mature form (25 kDa) but, depending on the tissue and isolation procedure, small amounts of the immature unprocessed form (40 kDa) and putative oligomers (50, 75 and 100 kDa) may be observed by immunoblotting using an antibody specific to the C-terminal sequence of VpVAN. The VpVAN protein is localized within chloroplasts and re-differentiated chloroplasts termed phenyloplasts, as monitored during the process of pod development. Isolated chloroplasts were shown to convert [14C]phenylalanine and [14C]cinnamic acid into [14C]vanillin glucoside, indicating that the entire vanillin de novo biosynthetic machinery converting phenylalanine to vanillin glucoside is present in the chloroplast.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.