Evidence map›Paper›PMID 29186078›Full record

ArticleMolecules (Basel, Switzerland)2017

Biological Properties of Low-Toxicity PLGA and PLGA/PHB Fibrous Nanocomposite Implants for Osseous Tissue Regeneration. Part I: Evaluation of Potential Biotoxicity.

Izabella Krucińska, Bogusława Żywicka, Agnieszka Komisarczyk, Maria Szymonowicz, Stanisława Kowalska, Ewa Zaczyńska, Marcin Struszczyk, Anna Czarny, Piotr Jadczyk, Barbara Umińska-Wasiluk and 2 more

Registry-linked trialAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03474900 (Elastic Stable Intramedullary Nailing of Forearm Shaft Fractures by Titanium Compared With Biodegradable Nails), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03474900 nacompletednot on this map

Elastic Stable Intramedullary Nailing of Forearm Shaft Fractures by Titanium Compared With Biodegradable Nails: Results of a Prospective Randomized Trial in Children With at Least Two Years of Follow-up

TypeinterventionalSponsorJaakko SinikumpuRan2011 to 2018Enrolled35ConditionsForearm FractureArmsPLGA implant, Bioretec ltd. Finland, Titanium elastic stable nail
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Biodegradable Polymers in Veterinary Medicine-A Review.Molecules (Basel, Switzerland) · 2024
    Review
  4. Polymers · 2021
    Review
  5. Surface-Modified Poly(l-lactide-International journal of molecular sciences · 2020
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Izabella KrucińskaDepartment of Material and Commodity Sciences and Textile Metrology, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz, Poland. izabella.krucinska@p.lodz.pl.
Bogusława ŻywickaDepartment of Experimental Surgery and Biomaterials Research, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland. boguslawa.zywicka@umed.wroc.pl.
Agnieszka KomisarczykDepartment of Material and Commodity Sciences and Textile Metrology, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz, Poland. agnieszka.komisarczyk@p.lodz.pl.
Maria SzymonowiczDepartment of Experimental Surgery and Biomaterials Research, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland. maria.szymonowicz@umed.wroc.pl.
Stanisława KowalskaDepartment of Material and Commodity Sciences and Textile Metrology, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz, Poland. skowal@p.lodz.pl.
Ewa ZaczyńskaInstitute of Immunology and Experimental Therapy, Polish Academy of Sciences, RudollfaWeigla 12, 53-114 Wroclaw, Poland. ezacz@iitd.pan.wroc.pl.
Marcin StruszczykDepartment of Material and Commodity Sciences and Textile Metrology, Technical University of Lodz, Zeromskiego 116, 90-924 Lodz, Poland. marcin.struszczyk@hotmail.com.
Anna CzarnyInstitute of Immunology and Experimental Therapy, Polish Academy of Sciences, RudollfaWeigla 12, 53-114 Wroclaw, Poland. czarny@iitd.pan.wroc.pl.
Piotr JadczykDepartment of Sanitary Biology and Ecotechnics, Wroclaw University of Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland. piotr.jadczyk@pwr.edu.pl.
Barbara Umińska-WasilukDepartment of Sanitary Biology and Ecotechnics, Wroclaw University of Technology, Wybrzeze Wyspianskiego 27, 50-370 Wroclaw, Poland. barbara.uminska-wasiluk@pwr.edu.pl.
Zbigniew RybakDepartment of Experimental Surgery and Biomaterials Research, Wroclaw Medical University, Pasteura 1, 50-367 Wroclaw, Poland. zbigniew.rybak@umed.wroc.pl.
Marek KowalczukCentre of Polymer and Carbon Materials of the Polish Academy of Sciences, MariiSkłodowskiej-Curie 34, 41-819 Zabrze, Poland. marek.kowalczuk@cmpw-pan.edu.pl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In response to the demand for new implant materials characterized by high biocompatibility and bioresorption, two prototypes of fibrous nanocomposite implants for osseous tissue regeneration made of a newly developed blend of poly(l-lactide-

Indexed as

Absorbable ImplantsBone RegenerationHydroxybutyratesNanocompositesPolyestersTissue ScaffoldsAnimalsBiomarkersCell LineCell SurvivalHumansLactic AcidMicePolyglycolic AcidPolyhydroxybutyratesPolylactic Acid-Polyglycolic Acid CopolymerBiomarkersHydroxybutyratesLactic AcidPHB protein, humanpoly-beta-hydroxybutyratePolyestersPolyglycolic AcidPolyhydroxybutyratesPolylactic Acid-Polyglycolic Acid CopolymerProhibitinsbiodegradationbiotoxicitybone implantcytotoxicityencapsulated growth factorgenotoxicityhemocompatability">l-lactide-co-glycolide)nonwoven fabricspoly(synthetic poly([R,S]-3-hydroxybutyrate)

Identifiers

PMID29186078
PMCPMC6149750

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.