Evidence map›Paper›PMID 29185486›Full record

ArticleScientific reports2017

Metabolomics profiling reveals different patterns in an animal model of asphyxial and dysrhythmic cardiac arrest.

Dimitrios Varvarousis, Theodoros Xanthos, Giulio Ferino, Antonio Noto, Nicoletta Iacovidou, Massimo Mura, Paola Scano, Athanasios Chalkias, Apostolos Papalois, Fabio De-Giorgio and 7 more

Abstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
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  7. Integrating rSOResuscitation plus · 2024
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  20. Forensic NMR metabolomics: one more arrow in the quiver.Metabolomics : Official journal of the Metabolomic Society · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Dimitrios VarvarousisMedical School, National and Kapodistrian University of Athens, Athens, Greece.
Theodoros XanthosEuropean University Cyprus, Nicosia, Cyprus.
Giulio FerinoDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Antonio NotoDepartment of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Nicoletta IacovidouAretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Massimo MuraMetabolic diseases Laboratory, Children Hospital "A. Cao", Cagliari, Italy.
Paola ScanoDepartment of Chemical and Geological Sciences, University of Cagliari, Cagliari, Italy.
Athanasios ChalkiasMedical School, National and Kapodistrian University of Athens, Athens, Greece.
Apostolos PapaloisExperimental-Research Center ELPEN Pharmaceutical, Athens, Greece.
Fabio De-GiorgioPublic Health Institute, Catholic University of Rome, Rome, Italy.
Alfonso BaldiDepartment of Environmental, Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Caserta, Italy.
Paolo MuraDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Chryssoula StaikouAretaieio Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Matteo StoccheroS-IN, Soluzioni Informatiche S.r.l., Vicenza, Italy.
Gabriele FincoDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Ernesto d'AlojaDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.
Emanuela LocciDepartment of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy. elocci@unica.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiac arrest (CA) is not a uniform condition and its pathophysiology strongly depends on its cause. In this work we have used a metabolomics approach to study the dynamic metabolic changes occurring in the plasma samples of a swine model following two different causes of CA, namely asphyxia (ACA) and ventricular fibrillation (VFCA). Plasma samples were collected at baseline and every minute during the experimental phases. In order to identify the metabolomics profiles characterizing the two pathological entities, all samples were analysed by

Indexed as

AnimalsArrhythmias, CardiacAsphyxiaChromatography, LiquidFemaleHeart ArrestMetabolomicsSwineTandem Mass SpectrometryVentricular Fibrillation

Identifiers

PMID29185486
PMCPMC5707403

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.