Evidence map›Paper›PMID 29184887›Full record

ReviewFrontiers in molecular biosciences2017

Weak Molecular Interactions in Clathrin-Mediated Endocytosis.

Sarah M Smith, Michael Baker, Mary Halebian, Corinne J Smith

Abstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  12. Cells · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sarah M SmithSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Michael BakerSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Mary HalebianSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.
Corinne J SmithSchool of Life Sciences, University of Warwick, Coventry, United Kingdom.

Funding

Biotechnology and Biological Sciences Research Council BB/L018888/1Biotechnology and Biological Sciences Research Council BB/N008391/1
6 · The paper itself

Abstract

Clathrin-mediated endocytosis is a process by which specific molecules are internalized from the cell periphery for delivery to early endosomes. The key stages in this step-wise process, from the starting point of cargo recognition, to the later stage of assembly of the clathrin coat, are dependent on weak interactions between a large network of proteins. This review discusses the structural and functional data that have improved our knowledge and understanding of the main weak molecular interactions implicated in clathrin-mediated endocytosis, with a particular focus on the two key proteins: AP2 and clathrin.

Indexed as

adaptor-proteinclathrinendocytosismolecular interactionsstructural biology

Identifiers

PMID29184887
PMCPMC5694535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.