ArticleAnnals of surgical treatment and research2017
Prognostic factors after curative resection hepatocellular carcinoma and the surgeon's role.
Article in Annals of surgical treatment and research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- An evaluation of the effectiveness of 3D virtual imaging combined with intraoperative ultrasonography to guide liver staining in anatomic segmental hepatectomy.Global health & medicine · 2025Article
- Review
- Predictors for 30-day mortality in hepatocellular carcinoma patients undergoing liver resection.Narra J · 2024Article
- Limited Generalizability of Retrospective Single-Center Cohort Study in Comparison to Multicenter Cohort Study on Prognosis of Hepatocellular Carcinoma.Journal of hepatocellular carcinoma · 2024Article
- Preoperative lymphocyte-to-C-reactive protein ratio predicts hepatocellular carcinoma recurrence after surgery.Annals of surgical treatment and research · 2022Article
- Probabilistic ratiocination of hepatocellular carcinoma after resection: evaluation of expected to be promising approaches.Annals of translational medicine · 2021Article
- Operation start time and long-term outcome of hepatocellular carcinoma after curative hepatic resection.Annals of surgical treatment and research · 2020Article
- Perioperative blood transfusion has distinct postsurgical oncologic impact on patients with different stage of hepatocellular carcinoma.BMC cancer · 2020Article
- Staged partial hepatectomy versus transarterial chemoembolization for the treatment of spontaneous hepatocellular carcinoma rupture: a multicenter analysis in Korea.Annals of surgical treatment and research · 2019Article
- Preoperative Neutrophil-to-Lymphocyte Ratio Plus Platelet-to-Lymphocyte Ratio Predicts the Outcomes after Curative Resection for Hepatocellular Carcinoma.International journal of hepatology · 2019Article
- Prognostic factors in patients with HBV-related hepatocellular carcinoma following hepatic resection.Infectious agents and cancer · 2018Article
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6 authors.
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Abstract
purposePatient, surgical, and tumor factors affect the outcome after surgical resection for hepatocellular carcinoma (HCC). The surgical factors are only modifiable by the surgeon. We reviewed our experience with curative resection for HCC in terms of surgical factors.
methodsAfter analyses of the prospectively collected clinical data of 256 consecutive patients undergoing surgical resection for HCC, prognostic factors for disease-free survival (DFS) and overall survival (OS) were identified; all patients were stratified by tumor diameters > or <5 cm and their outcomes were compared.
resultsMultivariate analyses showed that microvascular invasion, estimated blood loss, blood transfusion, and the number of tumors were independent adverse prognostic factors for DFS, whereas microvascular invasion, serum alpha fetoprotein, and tumor diameter were independent adverse prognostic factors for OS. Blood transfusion had borderline significance (P = 0.076). After stratification by tumor diameter, blood transfusion was only associated with poor DFS and OS in patients with tumor diameters > 5 cm.
conclusionTumor recurrence after liver resection for HCC depends on tumor status, bleeding, and transfusions, which subsequently lead to poor patient survival. Surgeons can help improve the prognosis of patients by minimizing blood loss and transfusion, particularly in patients with larger tumors.
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