Evidence map›Paper›PMID 29184675›Full record

ReviewJournal of thoracic disease2017

Possible application of circulating free tumor DNA in non-small cell lung cancer patients.

Niki Karachaliou, Aaron E Sosa, Miguel Angel Molina, Margarita Centelles Ruiz, Rafael Rosell

Abstract readReview
In one paragraph

Review in Journal of thoracic disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Liquid biopsy using extracellular vesicle-derived DNA in lung adenocarcinoma.Journal of pathology and translational medicine · 2020
    Review
  5. Article
  6. Review
  7. Review
  8. Liquid biopsy for lung cancer early detection.Journal of thoracic disease · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Niki KarachaliouInstituto Oncológico Dr Rosell (IOR), University Hospital Sagrat Cor, Barcelona, Spain.
Aaron E SosaInstituto Oncológico Dr Rosell (IOR), University Hospital Sagrat Cor, Barcelona, Spain.
Miguel Angel MolinaPangaea Oncology, Laboratory of Molecular Biology, Quirón-Dexeus University Institute, Barcelona, Spain.
Margarita Centelles RuizMedical Oncology Department, University Hospital Sagrat Cor, Barcelona, Spain.
Rafael RosellInstituto Oncológico Dr Rosell (IOR), University Hospital Sagrat Cor, Barcelona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liquid biopsies have been heralded as a game changer in cancer management. Blood tests offer a minimally invasive, safe and sensitive complementary (or even alternative) approach for tissue biopsies. With lung cancer being the second most commonly diagnosed cancer and the leading cause of cancer deaths worldwide, due to the limitations of tissue sampling, liquid biopsies must urgently materialize in the clinic. In this short review, we will present the current applications of cell-free DNA (cfDNA) in lung cancer management, emphasizing on our own experience and previous work. We will also shortly comment on the challenges and need for a coordinated collaboration combining disciplines and sectors (from academia to health economies) in order to accelerate liquid biopsy development in lung cancer and other cancers.

Indexed as

cell-free DNA (cfDNA)epidermal growth factor receptor (EGFR)liquid biopsiesLung cancer

Identifiers

PMID29184675
PMCPMC5676104

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.