Evidence map›Paper›PMID 29184554›Full record

ArticleFrontiers in immunology2017

IL-17 and TNF-α Are Key Mediators of

Safa Alnahas, Stefanie Hagner, Hartmann Raifer, Ayse Kilic, Georg Gasteiger, Reinier Mutters, Anne Hellhund, Immo Prinz, Olaf Pinkenburg, Alexander Visekruna and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 84 citations in OpenAlex.

  1. The Human Respiratory Microbiome: Current Understandings and Future Directions.American journal of respiratory cell and molecular biology · 2023
    Pooled it
  2. Review
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  16. Impact of Exposomes on Ocular Surface Diseases.International journal of molecular sciences · 2023
    Review
  17. Review
  18. Article
  19. Article
  20. Asthma-associated bacterial infections: Are they protective or deleterious?The journal of allergy and clinical immunology. Global · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Safa AlnahasInstitute of Medical Microbiology and Hospital Hygiene, University of Marburg, Marburg, Germany.
Stefanie HagnerInstitute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Member of the German Center for Lung Research, University of Marburg, Marburg, Germany.
Hartmann RaiferInstitute of Medical Microbiology and Hospital Hygiene, University of Marburg, Marburg, Germany.
Ayse KilicInstitute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Member of the German Center for Lung Research, University of Marburg, Marburg, Germany.
Georg GasteigerInstitute of Medical Microbiology and Hygiene, FZI Research Center for Immunotherapy, University of Mainz Medical Center, Mainz, Germany.
Reinier MuttersInstitute of Medical Microbiology and Hospital Hygiene, University of Marburg, Marburg, Germany.
Anne HellhundInstitute of Medical Microbiology and Hospital Hygiene, University of Marburg, Marburg, Germany.
Immo PrinzInstitute of Immunology, Hannover Medical School, Hannover, Germany.
Olaf PinkenburgInstitute of Medical Microbiology and Hospital Hygiene, University of Marburg, Marburg, Germany.
Alexander VisekrunaInstitute of Medical Microbiology and Hospital Hygiene, University of Marburg, Marburg, Germany.
Holger GarnInstitute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Member of the German Center for Lung Research, University of Marburg, Marburg, Germany.
Ulrich SteinhoffInstitute of Medical Microbiology and Hospital Hygiene, University of Marburg, Marburg, Germany.
Philipps University of Marburg · DEGerman Center for Lung Research · DEInstitute of Medical Microbiology and Hygiene · DEMedizinische Hochschule Hannover · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations of the airway microbiome are often associated with pulmonary diseases. For example, detection of the bacterial pathogen

Indexed as

exacerbation of allergic reactionsexacerbation of pulmonary inflammationIL-17infection and allergymicrobial exacerbation of pulmonary inflammationMoraxellaceae infectionspulmonary inflammationTNF-α

Identifiers

PMID29184554
PMCPMC5694487
OpenAlexW2768701148

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.