ReviewFrontiers in endocrinology2017
Sex Differences in the Regulation of Offensive Aggression and Dominance by Arginine-Vasopressin.
Review in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 87 citations in OpenAlex.
- Coordination of social behaviors by the bed nucleus of the stria terminalis.The European journal of neuroscience · 2022Pooled it
- Early-life environmental enrichment reduces anxiety and induces sex-dependent neuroplasticity in hypothalamic oxytocin and vasopressin neurons.Journal of neuroendocrinology · 2026Article
- Serotonin deficiency caused by inactivation of Tph2 in mice leads to widespread sex-dependent changes in cerebral oxidative metabolic activity.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Dichotomous Regulation of Social Behaviors by Nucleus Accumbens Neurons in Female and Male Syrian Hamsters.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Nonlinear and sex-specific effects of V1aR deletion on juvenile social behavior.Frontiers in endocrinology · 2026Article
- Sex differences in the neural circuitry of aggression.bioRxiv : the preprint server for biology · 2025Article
- Sex differences in structural and receptor mRNA expression in the ventral anterior cingulate cortex and a potential role of perineuronal nets in monogamous pair bond establishment (Peromyscus californicus).Biology of sex differences · 2025Article
- A survey of hypothalamic phenotypes identifies molecular and behavioral consequences of MYT1L haploinsufficiency in male and female mice.Hormones and behavior · 2025Article
- Sex Differences in Brain Transcriptomes of Juvenile Cynomolgus Macaques.Biomolecules · 2025Article
- Hormonal changes in first-time human fathers in relation to paternal investment.Hormones and behavior · 2025Article
- Hypothalamic resting-state functional connectivity and self-evaluated aggression in young adults.Journal of psychiatric research · 2025Article
- Unraveling sex differences in maternal and paternal care impacts on social behaviors and neurobiological responses to early-life adversity.Frontiers in neuroendocrinology · 2025Review
- Hypothalamic connectivities and self-evaluated aggression in young adults.bioRxiv : the preprint server for biology · 2024Article
- The effects of different types of social interactions on the electrophysiology of neurons in the nucleus accumbens in rodents.Neuroscience and biobehavioral reviews · 2024Review
- Hypothalamic vasopressin sex differentiation is observed by embryonic day 15 in mice and is disrupted by the xenoestrogen bisphenol A.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Connectivity and molecular profiles of Foxp2- and Dbx1-lineage neurons in the accessory olfactory bulb and medial amygdala.The Journal of comparative neurology · 2024Article
- Activation of arginine vasopressin receptor 1a reduces inhibitory synaptic currents at reciprocal synapses in the mouse accessory olfactory bulb.Frontiers in cellular neuroscience · 2024Article
- Understanding Others' Distress Through Past Experiences: The Role of Memory Engram Cells in Observational Fear.Advances in neurobiology · 2024Review
- TheFrontiers in psychology · 2024Article
- Characterization of social hierarchy formation and maintenance in same-sex, group-housed male and female C57BL/6 J mice.Hormones and behavior · 2024Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Arginine-vasopressin (AVP) plays a critical role in the regulation of offensive aggression and social status in mammals. AVP is found in an extensive neural network in the brain. Here, we discuss the role of AVP in the regulation of aggression in the limbic system with an emphasis on the critical role of hypothalamic AVP in the control of aggression. In males, activation of AVP V1a receptors (V1aRs) in the hypothalamus stimulates offensive aggression, while in females activation of V1aRs inhibits aggression. Serotonin (5-HT) also acts within the hypothalamus to modulate the effects of AVP on aggression in a sex-dependent manner. Activation of 5-HT1a receptors (5-HT1aRs) inhibits aggression in males and stimulates aggression in females. There are also striking sex differences in the mechanisms underlying the acquisition of dominance. In males, the acquisition of dominance is associated with the activation of AVP-containing neurons in the hypothalamus. By contrast, in females, the acquisition of dominance is associated with the activation of 5-HT-containing neurons in the dorsal raphe. AVP and 5-HT also play critical roles in the regulation of a form of social communication that is important for the maintenance of dominance relationships. In both male and female hamsters, AVP acts
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.