ReviewClinics in colon and rectal surgery2017
The Perfect Total Mesorectal Excision Obviates the Need for Anything Else in the Management of Most Rectal Cancers.
Review in Clinics in colon and rectal surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Efficacy and safety of transanal endoscopic microsurgery for early rectal cancer: a meta-analysis.Frontiers in oncology · 2025Pooled it
- Comparison of the transanal surgical techniques for local excision of rectal tumors: a network meta-analysis.International journal of colorectal disease · 2020Pooled it
- Global updates in the treatment of gastric cancer: a systematic review. Part 1: staging, classification and surgical treatment.Updates in surgery · 2020Pooled it
- Artificial Intelligence-Guided Total Mesorectal Excision: Development of a Deep Learning Model to Identify the Pelvic Fascial Plane Anatomy.Annals of gastroenterological surgery · 2025Article
- Simultaneous integrated boost to lateral pelvic lymph nodes during chemoradiotherapy in high-risk rectal cancer.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2025Article
- Artificial intelligence-enhanced navigation for nerve recognition and surgical education in laparoscopic colorectal surgery.Surgical endoscopy · 2025Article
- AI-based visualization of loose connective tissue as a dissectable layer in gastrointestinal surgery.Scientific reports · 2025Article
- [Treatment strategies for recurrent rectal cancer].Chirurgie (Heidelberg, Germany) · 2024Review
- Perioperative outcomes of laparoscopic low anterior resection using ArtiSentialTechniques in coloproctology · 2024Article
- Clinical Tools for Rectal Cancer Response Assessment following Neoadjuvant Treatment in the Era of Organ Preservation.Cancers · 2023Review
- Quantitative assessment of the microstructure of the mesorectum with different prognostic statuses by intravoxel incoherent motion diffusion-weighed magnetic resonance imaging.BMC gastroenterology · 2022Article
- The Role of Simultaneous Integrated Boost in Locally Advanced Rectal Cancer Patients with Positive Lateral Pelvic Lymph Nodes.Cancers · 2022Article
- The "terminal line": a novel sign for the identification of distal mesorectum end during TME for rectal cancer.Gastroenterology report · 2022Article
- Automated segmentation by deep learning of loose connective tissue fibers to define safe dissection planes in robot-assisted gastrectomy.Scientific reports · 2021Article
- Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as a Liquid Biopsy Marker in Colorectal Cancer.Cancers · 2021Review
- Neoadjuvant Pelvic Radiotherapy in the Management of Rectal Cancer with Synchronous Liver Metastases: Is It Worth It?Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2021Review
- Endoscopic and MRI response evaluation following neoadjuvant treatment for rectal cancer: a pictorial review with matched MRI, endoscopic, and pathologic examples.Abdominal radiology (New York) · 2021Review
- Education and Training in Transanal Endoscopic Surgery and Transanal Total Mesorectal Excision.Clinics in colon and rectal surgery · 2021Review
- Optimal Complete Rectum Mobilization Focused on the Anatomy of the Pelvic Fascia and Autonomic Nerves: 30 Years of Experience at Severance Hospital.Yonsei medical journal · 2021Review
- Gastric equivalent of the 'Holy Plane' to standardize the surgical concept of stomach cancer to mesogastric excision: updating Jamieson and Dobson's historic schema.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This article discusses the local control of primary rectal cancer and its locoregional spread in the light of modern advances. In recent years, the use of neoadjuvant chemoradiation has spread widely. However, its true benefit is not always balanced with its morbidities. Often total mesorectal excision (TME) is the best option. We will discuss the indications for immediate surgery for chemoradiation in advance and the importance of a delay in the management plan. To understand this selection, it is mandatory to know the true extent of tissue at risk for tumor dissemination and spread. Considering that TME may be enough for many patients and that most local recurrences are failures of surgical technique we introduce a new concept of total mesorectal irradiation. This exploits the new reality that precise, focused neoadjuvant therapy can offer a better response with fewer complications. Together these important changes in cancer board (multidisciplinary team) planning can also offer selected patients complete control of their cancer with no need for surgery.
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