Evidence map›Paper›PMID 29184260›Full record

ArticleIranian journal of medical sciences2017

Topical Effects of Artemisia Absinthium Ointment and Liniment in Comparison with Piroxicam Gel in Patients with Knee Joint Osteoarthritis: A Randomized Double-Blind Controlled Trial.

Zahra Basiri, Fatemeh Zeraati, Farzaneh Esna-Ashari, Farshid Mohammadi, Keyvan Razzaghi, Malihe Araghchian, Shirin Moradkhani

Abstract read
In one paragraph

Article in Iranian journal of medical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Addiction & health · 2025
    Article
  3. Review
  4. The dietary supplement CyplexinolJournal of clinical and translational research · 2023
    Article
  5. Review
  6. Article
  7. Oxidative medicine and cellular longevity · 2022
    Review
  8. Research Advances on Health Effects of EdibleFoods (Basel, Switzerland) · 2020
    Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zahra BasiriDepartment of Internal Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Fatemeh ZeraatiMedicinal Plants and Natural Product Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Farzaneh Esna-AshariDepartment of Community Medicine, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Farshid MohammadiSchool of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
Keyvan RazzaghiMedicinal Plants and Natural Product Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.
Malihe AraghchianDepartment of Pharmacology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran.
Shirin MoradkhaniMedicinal Plants and Natural Product Research Center, Hamadan University of Medical Sciences, Hamadan, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPain alleviation and improvement of functional status are the main objectives in the treatment of osteoarthritis.

methodsIn total, 90 outpatients aged 30-70 years with the diagnosis of primary osteoarthritis in at least one knee were enrolled in a randomized double-blind clinical trial. The patients referred to the Rheumatology Clinic at Shahid Beheshti Hospital in Hamadan province during 2012-2013. The patients were randomly assigned into three groups, 30 patients per group, and respectively received AA ointment (AAO) 3%, AA liniment (AAL) 3%, and PG; three times daily (TID) for 4 weeks. The patients were visited at baseline, week 4, and week 6. The effectiveness criteria were pain severity which was assessed with a 10-point visual analog scale (VAS), the Western Ontario and McMaster Universities osteoarthritis index (WOMAC) for total pain score (WTPS), total physical function score (WTPFS), and total stiffness score (WTSS). Repeated measure ANOVA, paired

resultsAll groups had similar patient demographics. The administration of PG significantly improved all tested criteria with no recurrence after discontinuing the treatment protocol. AAO alleviated all tested factors except for WTSS. Alleviation was comparable to PG. AAL only reduced pain factors (VAS, WTPS) in week 4 with recurrence in week 6.

conclusionAdministration of

Indexed as

Artemisia absinthiumOsteoarthritisPiroxicam

Identifiers

PMID29184260
PMCPMC5684373

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.