Evidence map›Paper›PMID 29184210›Full record

ReviewNature neuroscience2017

Thalamic functions in distributed cognitive control.

Michael M Halassa, Sabine Kastner

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 277 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
277citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

277 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Cephalopod Behavior: From Neural Plasticity to Consciousness.Frontiers in systems neuroscience · 2021
    Pooled it
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  11. Article
  12. Thalamic Nuclei Atrophy in Type 1 Diabetes Mellitus Across Disease Duration.Journal of magnetic resonance imaging : JMRI · 2026
    Article
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  18. Review
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217 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Michael M HalassaDepartment of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA. mhalassa@mit.edu.ORCID http://orcid.org/0000-0003-1386-0336
Sabine KastnerPrinceton Neuroscience Institute, Princeton University, Princeton, New Jersey, USA.

Funding

Project 5: ComputationalP50MH109429 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI STEPHANIE Ruggiano JONES · 2017 to 2026
$25.3M
Functions of the Thalamus in Perception and CognitionR01EY017699 · NEI · PRINCETON UNIVERSITY · PI SABINE KASTNER · 2007 to 2026
$6.4M
Neural mechanisms of attentionR01MH064043 · NIMH · PRINCETON UNIVERSITY · PI KASTNER, SABINE, KNIGHT, ROBERT THOMAS · 2002 to 2020
$5.2M
NEI NIH HHS R01 EY017699NIMH NIH HHS P50 MH109429NIMH NIH HHS R01 MH064043
6 · The paper itself

Abstract

Cognition can be conceptualized as a set of algorithmic control functions whose real-time deployment determines how an organism stores and uses information to guide thought and action. A subset of these functions is required for goal-directed selection and amplification of sensory signals-broadly referred to as attention-and for its flexible control and its interaction with processes such as working memory and decision making. While the contribution of recurrent cortical microcircuits to cognition has been extensively studied, the role of the thalamus is just beginning to be elucidated. Here we highlight recent studies across rodents and primates showing how thalamus contributes to attentional control. In addition to high-fidelity information relay to or between cortical regions, thalamic circuits shift and sustain functional interactions within and across cortical areas. This thalamic process enables rapid coordination of spatially segregated cortical computations, thereby constructing task-relevant functional networks. Because such function may be critical for cognitive flexibility, clarifying its mechanisms will likely expand our basic understanding of cognitive control and its perturbation in disease.

Indexed as

AnimalsAttentionCerebral CortexCognitionHumansThalamus

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.