ArticleNature neuroscience2017
A craniofacial-specific monosynaptic circuit enables heightened affective pain.
Article in Nature neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 115 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
115 citing papers in PubMed.
- Distinct parafascicular neuronal ensembles mediate the sensory and affective dimensions of trigeminal neuralgia.The Journal of clinical investigation · 2026Article
- Comparative Electrophysiological Analysis of Trigeminal and Dorsal Root Ganglion Neurons in Mice.eNeuro · 2026Article
- Review
- LPA/LPAR signaling drives temporomandibular disorders-like pain through regulating the expression and sensitization of PIEZO2.Science advances · 2026Article
- Opioid- and NMDA-receptor-dependent neural plasticity mediates long-term analgesia from motor cortical stimulation.bioRxiv : the preprint server for biology · 2026Article
- Early life stress induces brain-wide electrical network predisposition to migraine.The journal of headache and pain · 2026Article
- Trigeminal neuralgia: from clinical challenges to molecular insights.The journal of headache and pain · 2026Review
- Substance P and somatostatin neurons limit facial itch by recruiting distinct nociceptive circuits in the brainstem.Communications biology · 2026Article
- A Tac1-Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Mechanisms of the trigeminal-lateral parabrachial-rostroventral medullary circuits involved in experimental occlusal interference induced chronic orofacial pain.The journal of headache and pain · 2026Article
- The posterior capsular central amygdala showing synaptic coactivation with nociplastic pain-associated parabrachial neurons in mice.iScience · 2025Article
- Mechanistic intersections between migraine and major depressive disorder.The journal of headache and pain · 2025Review
- Distinct Neural Mechanisms in the Propagation of Itch in the Face and Body.Research square · 2025Article
- Estrogens produced within the central amygdala inhibit varicella zoster-induced orofacial pain.Journal of neuroendocrinology · 2025Article
- Symptomatic irreversible pulpitis and other orofacial pain: overcoming challenges in diagnosis and management.British dental journal · 2025Review
- Afferent Projections to the Calca/CGRP-Expressing Parabrachial Neurons in Mice.The Journal of comparative neurology · 2025Article
- Delineation of the trigeminal-lateral parabrachial-central amygdala tract in humans.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- What Links Sleep and Neuropathic Pain?: A Literature Review on the Neural Circuits for Sleep and Pain Control.Nature and science of sleep · 2025Review
- Neural mechanism of trigeminal nerve stimulation recovering defensive arousal responses in traumatic brain injury.Theranostics · 2025Article
- General anesthesia activates a central anxiolytic center in the BNST.Cell reports · 2024Article
55 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
11 authors.
Funding
Abstract
Humans often rank craniofacial pain as more severe than body pain. Evidence suggests that a stimulus of the same intensity induces stronger pain in the face than in the body. However, the underlying neural circuitry for the differential processing of facial versus bodily pain remains unknown. Interestingly, the lateral parabrachial nucleus (PB
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.