Evidence map›Paper›PMID 29183977›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Osmosensing by the bacterial PhoQ/PhoP two-component system.

Jing Yuan, Fan Jin, Timo Glatter, Victor Sourjik

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed.

  1. Review
  2. Article
  3. Discovery of HAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  4. Hijacking competitor-derived signals: RcsB/C drivesApplied and environmental microbiology · 2026
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  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
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  11. Analysis of stress-induced small proteins inbioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Review
  19. Review
  20. Review

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing YuanMax Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany; jing.yuan@synmikro.mpi-marburg.mpg.de victor.sourjik@synmikro.mpi-marburg.mpg.de.
Fan JinMax Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany.
Timo GlatterMax Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany.
Victor SourjikMax Planck Institute for Terrestrial Microbiology, 35043 Marburg, Germany; jing.yuan@synmikro.mpi-marburg.mpg.de victor.sourjik@synmikro.mpi-marburg.mpg.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PhoQ/PhoP two-component system plays an essential role in the response of enterobacteria to the environment of their mammalian hosts. It is known to sense several stimuli that are potentially associated with the host, including extracellular magnesium limitation, low pH, and the presence of cationic antimicrobial peptides. Here, we show that the PhoQ/PhoP two-component systems of

Indexed as

Osmotic PressureEscherichia coliEscherichia coli ProteinsSalmonellaEscherichia coli ProteinsPhoP protein, E coliPhoQ protein, E colienterobacteriaosmolaritysignal transductionstress responsevirulence

Identifiers

PMID29183977
PMCPMC5740661

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.