Evidence map›Paper›PMID 29183961›Full record

SynthesisBMJ (Clinical research ed.)2017

Oral anticoagulants for prevention of stroke in atrial fibrillation: systematic review, network meta-analysis, and cost effectiveness analysis.

José A López-López, Jonathan A C Sterne, Howard H Z Thom, Julian P T Higgins, Aroon D Hingorani, George N Okoli, Philippa A Davies, Pritesh N Bodalia, Peter A Bryden, Nicky J Welton and 8 more

Erratum issued Registry-linked trialAbstract readSystematic ReviewNetwork Meta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03568890 (Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure. The ANDES Trial), which is not on this map. Cited by 267 papers, 22 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
267citing papers in PubMed, 22 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03568890 phase4active not recruitingnot on this mapstarted 2018, after this paper: background citation

Short-Term Anticoagulation Versus Antiplatelet Therapy for Preventing Device Thrombosis Following Left Atrial Appendage Closure. The ANDES Trial

TypeinterventionalSponsorCentre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de QuebecRan2018 to 2030Enrolled510ConditionsLeft Atrial Appendage Closure, Thrombosis, Stroke, TIAArmsRivaroxaban, dabigatran, apixaban, or edoxaban, Clopidogrel -75 mg/day, Low dose aspirin -80 to 125 mg/day-
3 · Its place in the literature

Who cites it

267 citing papers in PubMed, 22 syntheses or guidelines pooled it.

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207 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

18 authors.

José A López-LópezDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Jonathan A C SterneDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK jonathan.sterne@bristol.ac.uk.
Howard H Z ThomDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Julian P T HigginsDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Aroon D HingoraniFaculty of Population Health Sciences, University College London, London, UK.
George N OkoliDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Philippa A DaviesDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Pritesh N BodaliaUniversity College London Hospitals NHS Foundation Trust, London, UK.
Peter A BrydenDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Nicky J WeltonDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
William HollingworthDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Deborah M CaldwellDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Jelena SavovićDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Sofia DiasDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Chris SalisburyDepartment of Population Health Sciences, Bristol Medical School, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK.
Diane EatonAntiCoagulation Europe, Bromley, Kent, UK.
Annya Stephens-BoalThrombosis UK, Llanwrda, UK.
Reecha SofatFaculty of Population Health Sciences, University College London, London, UK.

Funding

Department of Health 11/92/17Department of Health 14/141/01
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Administration, OralAnticoagulantsAtrial FibrillationCost-Benefit AnalysisDrug CostsHemorrhageHumansQuality-Adjusted Life YearsRandomized Controlled Trials as TopicStrokeAnticoagulants

Identifiers

PMID29183961
PMCPMC5704695

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.