Evidence map›Paper›PMID 29183938›Full record

ReviewDevelopment (Cambridge, England)2017

Tension, contraction and tissue morphogenesis.

Natalie C Heer, Adam C Martin

Abstract readReview
In one paragraph

Review in Development (Cambridge, England), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Shape, Strain, and Stability: Epithelia Under High Strain.bioRxiv : the preprint server for biology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Reducing Cofilin dosage makes embryos resilient to heat stress.bioRxiv : the preprint server for biology · 2025
    Article
  15. Review
  16. Nanoscale dynamics of the cadherin-catenin complex bound to vinculin revealed by neutron spin echo spectroscopy.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  17. Regulation of intercellular viscosity by E-cadherin-dependent phosphorylation of EGFR in collective cell migration.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  18. Article
  19. Article
  20. Article

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Natalie C HeerDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.ORCID 0000-0002-6003-9981
Adam C MartinDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142, USA acmartin@mit.edu.ORCID 0000-0001-8060-2607

Funding

PRE-DOCTORAL TRAINING IN THE BIOLOGICAL SCIENCEST32GM007287 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BELL, STEPHEN P., KEATING, AMY E · 1985 to 2019
$40.8M
Investigating the generation of mechanical forces during tissue invaginationR01GM105984 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MARTIN, ADAM CHRISTOPHER · 2013 to 2021
$2.4M
NIGMS NIH HHS R01 GM105984NIGMS NIH HHS T32 GM007287
6 · The paper itself

Abstract

D'Arcy Thompson was a proponent of applying mathematical and physical principles to biological systems, an approach that is becoming increasingly common in developmental biology. Indeed, the recent integration of quantitative experimental data, force measurements and mathematical modeling has changed our understanding of morphogenesis - the shaping of an organism during development. Emerging evidence suggests that the subcellular organization of contractile cytoskeletal networks plays a key role in force generation, while on the tissue level the spatial organization of forces determines the morphogenetic output. Inspired by D'Arcy Thompson's

Indexed as

ActinsAnimalsBiomechanical PhenomenaCell MovementEpithelial CellsHumansIntercellular JunctionsModels, BiologicalMolecular Motor ProteinsMorphogenesisMuscle ContractionMyosinsActinsMolecular Motor ProteinsMyosinsActinContractilityMorphogenesisMyosinTension

Identifiers

PMID29183938
PMCPMC5769629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.