ArticleBiology open2018
Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function.
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Article in Biology open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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40citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
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Who cites it
40 citing papers in PubMed, 49 citations in OpenAlex.
- Epigenetic and chromatin remodeling mechanisms across cardiomyopathies: a comprehensive review.Epigenetics & chromatin · 2026Review
- A SWI/SNF-specific Ig-like domain, SWIFT, is a transcription factor binding platform.Science (New York, N.Y.) · 2026Article
- G protein GαThe Journal of biological chemistry · 2026Article
- System analysis links SMARCD3 regulons to growth signaling and MEK inhibitor response in everolimus-resistant ER+ breast cancer cells.Cell reports. Medicine · 2025Article
- Epigenetic Mechanisms in Heart Diseases.Reviews in cardiovascular medicine · 2025Review
- Smarce1 fine-tunes cardiomyocyte proliferation in the embryonic zebrafish heart.Frontiers in cell and developmental biology · 2025Article
- The multifaceted roles of BAF60 subunits in muscle: regulation of differentiation, reprogramming, and metabolic homeostasis.Frontiers in cell and developmental biology · 2025Review
- Epigenetics of cardiomyopathies: the next frontier.Heart failure reviews · 2025Review
- Regulatory Roles of SWI/SNF Chromatin Remodeling Complexes in Immune Response and Inflammatory Diseases.Clinical reviews in allergy & immunology · 2024Review
- The molecular mechanisms of cardiac development and related diseases.Signal transduction and targeted therapy · 2024Review
- Epigenetic Regulation of Mammalian Cardiomyocyte Development.Epigenomes · 2024Review
- Epigenetic determinants and non-myocardial signaling pathways contributing to heart growth and regeneration.Pharmacology & therapeutics · 2024Review
- SWI/SNF Complex in Vascular Smooth Muscle Cells and Its Implications in Cardiovascular Pathologies.Cells · 2024Review
- Epigenetic Regulation of Fibroblasts and Crosstalk between Cardiomyocytes and Non-Myocyte Cells in Cardiac Fibrosis.Biomolecules · 2023Review
- Cardiomyocyte proliferation is suppressed by ARID1A-mediated YAP inhibition during cardiac maturation.Nature communications · 2023Article
- Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development.Developmental cell · 2023Article
- Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens.Molecular cell · 2023Article
- A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.Nature cell biology · 2023Article
- The Current Therapeutic Role of Chromatin Remodeling for the Prognosis and Treatment of Heart Failure.Biomedicines · 2023Review
- Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma.Nature communications · 2023Article
Corrections and comments
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Authors and funding
12 authors at 6 institutions in 3 countries.
Xin SunProgram in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8 Canada.
Swetansu K HotaGladstone Institutes, San Francisco, CA, 94158 USA.
Yu-Qing ZhouThe Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, M5G 1X8 Canada.
Stefanie NovakDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724, USA.
Dario Miguel-PerezGladstone Institutes, San Francisco, CA, 94158 USA.
Danos ChristodoulouDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Christine E SeidmanDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
J G SeidmanDepartment of Genetics, Harvard Medical School, Boston, MA 02115, USA.
Carol C GregorioDepartment of Cellular and Molecular Medicine, University of Arizona, Tucson, AZ 85724, USA.
R Mark HenkelmanThe Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON, M5G 1X8 Canada.
Janet RossantProgram in Developmental and Stem Cell Biology, The Hospital for Sick Children, Toronto, ON, M5G 1X8 Canada.
Benoit G BruneauGladstone Institutes, San Francisco, CA, 94158 USA benoit.bruneau@gladstone.ucsf.edu.ORCID http://orcid.org/0000-0002-0804-7597
Gladstone Institutes · USUniversity of Toronto · CAHarvard University · USUniversity of Arizona · USBrigham and Women's Hospital · USHospital for Sick Children · CA
Funding
Administrative Coordinating Center: Cardiovascular Development and Pediatric Cardiac Genomics ConsortiaU01HL131003 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI CNOTA, JAMES, OLLBERDING, NICHOLAS J · 2016 to 2024
$54.8MTranscriptional Networks During Cardiac DifferentiationP01HL089707 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI SRIVASTAVA, DEEPAK · 2008 to 2017
$20.4MMOLECULAR AND CELLULAR BASIS OF CARDIOVASCULAR DISEASET32HL007731 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Brian L Black · 1992 to 2026
$12.4MThe Epigenetic Landscape of Heart DevelopmentU01HL098179 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BOYER, LAURIE A, BRUNEAU, BENOIT GAETAN · 2009 to 2014
$10.0MDeciphering the role of Lmod2 in thin filament length regulation and dilated cardiomyopathyR01HL123078 · NHLBI · UNIVERSITY OF ARIZONA · PI Carol C Gregorio, Shashank Shekhar · 2015 to 2026
$5.6MThe Epigenetic Landscape of Heart DevelopmentUM1HL098179 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BRUNEAU, BENOIT GAETAN, POLLARD, KATHERINE S. · 2015 to 2019
$4.7MChromatin remodeling complexes in heart developmentR01HL085860 · NHLBI · J. DAVID GLADSTONE INSTITUTES · PI BRUNEAU, BENOIT GAETAN · 2006 to 2010
$2.3MEXTRAMULAR RESEARCH FACILITIES CONSTRUCTIONC06RR018928 · NCRR · J. DAVID GLADSTONE INSTITUTES · PI MAHLEY, ROBERT W. · 2003 to 2003
$2.1MDeciphering the role of the RNA-binding protein, FXR1, in cardiac muscle assemblyR01HL108625 · NHLBI · UNIVERSITY OF ARIZONA · PI GREGORIO, CAROL C · 2012 to 2015
$1.9MNCRR NIH HHS C06 RR018928NHLBI NIH HHS P01 HL089707NHLBI NIH HHS R01 HL085860NHLBI NIH HHS R01 HL108625NHLBI NIH HHS R01 HL123078NHLBI NIH HHS T32 HL007731NHLBI NIH HHS U01 HL131003NHLBI NIH HHS UM1 HL098179
Abstract
How chromatin-remodeling complexes modulate gene networks to control organ-specific properties is not well understood. For example,
Indexed as
Chromatin remodelingEmbryoGene regulationHeart
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