Evidence map›Paper›PMID 29183897›Full record

ArticleBMJ case reports2017

Puzzling thyroid function test.

Nandhini Lakshmana Perumal, Jaya Prakash Sahoo, Sadishkumar Kamalanathan, Carla Moran

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nandhini Lakshmana PerumalDepartment of Endocrinology, Jawaharlal Institute of Post Graduate Medical Education, Puducherry, India.ORCID http://orcid.org/0000-0001-9444-1154
Jaya Prakash SahooDepartment of Endocrinology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
Sadishkumar KamalanathanDepartment of Endocrinology, Jawaharlal Institute of Post Graduate Medical Education and Research, Puducherry, India.
Carla MoranInstitute of Metabolic Science, University of Cambridge, Cambridge, UK.
Jawaharlal Institute of Post Graduate Medical Education and Research · INUniversity of Cambridge · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

A 13-½-year-old boy was referred to the Department of Endocrinology as a case of thyrotoxicosis for initiation of antithyroid medication. His chief complaint was a swelling in front of the neck, which was incidentally noted by his mother 2 weeks prior to presentation. He denied any history of symptoms suggestive of hyperthyroidism or ophthalmological involvement. His physical examination was unremarkable except for a grade 2 goitre. Thyroid function test revealed elevated free triiodothyronine and tetraiodothyronine in the face of an unsuppressed thyroid-stimulating hormone level. Technetium-99 uptake scan showed increased uptake indicating enhanced thyroid activity. However, he was clinically euthyroid. This raised the possibility of resistance to thyroid hormones, which was confirmed by documenting similar thyroid function test abnormalities in other members of his family and genetic testing. The family was reassured of the benign nature of the condition.

Indexed as

Thyroid Function TestsAdolescentDiagnosis, DifferentialGoiterHumansMaleTechnetiumThyroid GlandThyroid Hormone Resistance SyndromeThyroid HormonesTechnetiumThyroid Hormonespaediatricsthyroid disease

Identifiers

PMID29183897
PMCPMC5720324
OpenAlexW2770403744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.