Evidence map›Paper›PMID 29183368›Full record

Observational studyBMC surgery2017

Incidence of orthostatic hypotension and cardiovascular response to postoperative early mobilization in patients undergoing cardiothoracic and abdominal surgery.

Masatoshi Hanada, Yuichi Tawara, Takuro Miyazaki, Shuntaro Sato, Yosuke Morimoto, Masato Oikawa, Hiroshi Niwa, Kiyoyuki Eishi, Takeshi Nagayasu, Susumu Eguchi and 1 more

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04040647 (Tolerance of Early Mobilization and Ambulation the Day of Colorectal and Bariatric Surgery in an Enhanced Recovery Program), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04040647 completednot on this mapstarted 2019, after this paper: background citation

Tolerance of Early Mobilization and Ambulation the Day of Colorectal and Bariatric Surgery in an Enhanced Recovery Program

Typeobservational_patient_registrySponsorUniversity of LiegeRan2019 to 2020Enrolled88ConditionsAmbulation Difficulty, Colorectal Surgery, Bariatric SurgeryArmsmobilization and ambulation
3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Prognostic Implications of Orthostatic Hypotension in Elective Coronary Artery Bypass Grafting.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Observational
  5. Postoperative hypotension in gastric cancer patients: causes and clinical approaches.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Review
  6. Observational
  7. Article
  8. Review
  9. Observational
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Masatoshi HanadaCardiorespiratory Division, Department of Rehabilitation Medicine, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. mstshnd@nagasaki-u.ac.jp.ORCID http://orcid.org/0000-0002-6201-4921
Yuichi TawaraDepartment of Cardiopulmonary Rehabilitation Science, Unit of Rehabilitation Sciences, Graduate School of Biomedical Sciences, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Takuro MiyazakiDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Shuntaro SatoClinical Research Center, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Yosuke MorimotoCardiorespiratory Division, Department of Rehabilitation Medicine, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Masato OikawaCardiorespiratory Division, Department of Rehabilitation Medicine, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Hiroshi NiwaDivision of Thoracic Surgery, Respiratory Disease Center, Seirei Mikatahara General Hospital, 3458 Mikatahara, Hamamatsu, 433-8558, Japan.
Kiyoyuki EishiDepartment of Cardiovascular surgery, Nagasaki University Graduate School of Medicine, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Takeshi NagayasuDepartment of Surgical Oncology, Nagasaki University Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Susumu EguchiDepartment of Surgery, Nagasaki University Graduate School of Biomedical Science, Nagasaki, Japan, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Ryo KozuCardiorespiratory Division, Department of Rehabilitation Medicine, Nagasaki University Hospital, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan.
Nagasaki University · JPNagasaki University Hospital · JPSeirei Mikatabara General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn cardiothoracic and abdominal surgery, postoperative complications remain major clinical problems. Early mobilization has been widely practiced and is an important component in preventing complications, including orthostatic hypotension (OH) during postoperative management. We investigated cardiovascular response during early mobilization and the incidence of OH after cardiothoracic and abdominal surgery.

methodsIn this prospective observational study, we consecutively analyzed data from 495 patients who underwent elective cardiothoracic and abdominal surgery. We examined the incidence of OH, and the independent risk factors associated with OH during early mobilization after major surgery. Multivariate logistic regression was performed using various characteristics of patients to identify OH-related independent factors.

resultsOH was observed in 191 (39%) of 495 patients. The incidence of OH in cardiac, thoracic, and abdominal groups was 39 (33%) of 119, 95 (46%) of 208, and 57 (34%) of 168 patients, respectively. Male sex (OR 1.538; p = 0.03) and epidural anesthesia (OR 2.906; p < 0.001) were independently associated with OH on multivariate analysis.

conclusionsThese results demonstrate that approximately 40% patients experience OH during early mobilization after cardiothoracic and abdominal surgery. Sex was identified as an independent factor for OH during early mobilization after all three types of surgeries, while epidural anesthesia was only identified after thoracic surgery. Therefore, the frequent occurrence of OH during postoperative early mobilization should be recognized.

trial registrationUniversity hospital Medical Information Network Center (UMIN-CTR) number UMIN000018632 . (Registered on 1st October, 2008).

Indexed as

AbdomenAgedEarly AmbulationFemaleHumansHypotension, OrthostaticIncidenceMaleMiddle AgedPostoperative ComplicationsPostoperative PeriodProspective StudiesRisk FactorsThoracic Surgical ProceduresCardiothoracic and abdominal surgeryCardiovascular responsesEarly mobilizationOrthostatic hypotension

Identifiers

PMID29183368
PMCPMC5704500
OpenAlexW2769799091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.