Evidence map›Paper›PMID 29183321›Full record

ArticleBMC veterinary research2017

Effects of controlled hypoxemia or hypovolemia on global and intestinal oxygenation and perfusion in isoflurane anesthetized horses receiving an alpha-2-agonist infusion.

Klaus Hopster, Liza Wittenberg-Voges, Florian Geburek, Charlotte Hopster-Iversen, Sabine B R Kästner

Open access · goldAbstract read
In one paragraph

Article in BMC veterinary research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Klaus HopsterEquine Clinic, University of Veterinary Medicine Hanover, Foundation, Bünteweg 9, D-30559, Hanover, Germany. Klaus.hopster@gmx.de.ORCID http://orcid.org/0000-0003-0329-3083
Liza Wittenberg-VogesEquine Clinic, University of Veterinary Medicine Hanover, Foundation, Bünteweg 9, D-30559, Hanover, Germany.
Florian GeburekEquine Clinic, University of Veterinary Medicine Hanover, Foundation, Bünteweg 9, D-30559, Hanover, Germany.
Charlotte Hopster-IversenEquine Clinic, University of Veterinary Medicine Hanover, Foundation, Bünteweg 9, D-30559, Hanover, Germany.
Sabine B R KästnerEquine Clinic, University of Veterinary Medicine Hanover, Foundation, Bünteweg 9, D-30559, Hanover, Germany.
University of Veterinary Medicine Hannover, Foundation · DEWest Chester University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAim of this prospective experimental study was to assess effects of systemic hypoxemia and hypovolemia on global and gastrointestinal oxygenation and perfusion in anesthetized horses. Therefore, we anesthetized twelve systemically healthy warmblood horses using either xylazine or dexmedetomidine for premedication and midazolam and ketamine for induction. Anesthesia was maintained using isoflurane in oxygen with either xylazine or dexmedetomidine and horses were ventilated to normocapnia. During part A arterial oxygen saturation (SaO

resultsPart A: Reduction in arterial oxygenation resulted in a sigmoid decrease in central venous oxygen partial pressure. At SaO

conclusionsUnder isoflurane, intestinal tissue oxygenation remained at baseline when arterial oxygenation exceeded 80% and intestinal perfusion remained at baseline when MAP exceeded 51 mmHg and CI exceeded 40 mL/kg/min in this group of horses. TRIAL REGISTRY NUMBER: 33.14-42,502-04-14/1547.

Indexed as

Anesthesia, InhalationAnesthetics, InhalationAnimalsDexmedetomidineFemaleHeart RateHorsesHypovolemiaHypoxiaIntestinal MucosaIntestinesIsofluraneLaser-Doppler FlowmetryMaleOxygenProspective StudiesAnesthetics, InhalationDexmedetomidineIsofluraneOxygenXylazineGastrointestinal tractHypovolemiaHypoxemiaLaser Doppler flowmetryMicroperfusion

Identifiers

PMID29183321
PMCPMC5706348
OpenAlexW2768773762

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.