ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2018
Error-related Brain Activity as a Treatment Moderator and Index of Symptom Change during Cognitive-Behavioral Therapy or Selective Serotonin Reuptake Inhibitors.
Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Emotion-based brain mechanisms and predictors for SSRI and CBT treatment of anxiety and depression: a randomized trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2019Trial
- Exploring Longitudinal Associations Among Error-Related Negativity, Perception of Interpersonal Events, and Internalizing Symptoms in Female Adolescents.Research on child and adolescent psychopathology · 2026Article
- Psychometrics of drift-diffusion model parameters derived from the Eriksen flanker task: Reliability and validity in two independent samples.Cognitive, affective & behavioral neuroscience · 2025Article
- Agranular frontal cortical microcircuit underlying cognitive control in macaques.Frontiers in neural circuits · 2024Review
- Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration.Current psychiatry reports · 2022Review
- Neurocognitive Profiles in Adolescence Predict Subsequent Anxiety Trajectories During the COVID-19 Pandemic.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022Article
- Treatment-related changes towards normalization of the abnormal external signal processing in panic disorder.PloS one · 2020Article
- The impact of startle reactivity to unpredictable threat on the relation between bullying victimization and internalizing psychopathology.Journal of psychiatric research · 2019Review
- Error-related neural activity and alcohol use disorder: Differences from risk to remission.Progress in neuro-psychopharmacology & biological psychiatry · 2019Article
- Multidimensional imaging techniques for prediction of treatment response in major depressive disorder.Progress in neuro-psychopharmacology & biological psychiatry · 2019Article
- Electrophysiology as a theoretical and methodological hub for the neural sciences.Psychophysiology · 2019Review
- Impact of pubertal timing and depression on error-related brain activity in anxious youth.Developmental psychobiology · 2019Article
- Neural response to errors is associated with problematic alcohol use over time in combat-exposed returning veterans: An event-related potential study.Drug and alcohol dependence · 2018Article
- Targeting self-reported and neural error sensitivity: Short- and long-term effects of a one-week online intervention.International journal of clinical and health psychology : IJCHPArticle
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
Increased neural error monitoring, as measured by the error-related negativity (ERN), is a transdiagnostic neurobiological marker of anxiety. To date, little is known about whether the ERN can inform the choice between first-line anxiety disorder treatments and whether the ERN changes following treatment completion. The aim of the study was to therefore assess whether the ERN is a treatment moderator and index of symptom change during cognitive-behavioral therapy (CBT) or selective serotonin reuptake inhibitors (SSRIs). Participants included adult volunteers (M age=25.8±8.5; 67% female) with principal anxiety disorders (n=60) or no lifetime history of Axis I psychopathology (ie, healthy controls; n=26). A flanker task was used to elicit the ERN at baseline and 12 weeks later, following either CBT or SSRIs in the patient sample. Results indicated that baseline ERN was a significant treatment moderator such that a more enhanced baseline ERN was associated with greater reduction in anxiety symptoms within individuals who received CBT but not SSRIs. Results also revealed that the ERN increased pre- to post-treatment among patients randomized to SSRIs, but remained stable among patients randomized to CBT and healthy controls. Together, these novel findings highlight that ERN may help guide treatment decisions regarding engagement in CBT or SSRIs, especially among individuals with an enhanced ERN. The findings also suggest that SSRIs have the capacity to alter individual differences in the ERN, providing evidence that the ERN is not entirely static in patients with anxiety disorders.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.