ArticlemSystems
Increased Biosynthetic Gene Dosage in a Genome-Reduced Defensive Bacterial Symbiont.
Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed.
- Mining Microbial Dark Matter: Advanced Cultivation Techniques for Bioactive Compound Discovery.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Isolation of Ultra-SmallMicroorganisms · 2025Article
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- TRGdb: a universal resource for the exploration of taxonomically restricted genes in bacteria.Database : the journal of biological databases and curation · 2023Article
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- Review
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- Article
- Symbiotic Associations in Ascidians: Relevance for Functional Innovation and Bioactive Potential.Marine drugs · 2021Review
- The need to innovate sample collection and library generation in microbial drug discovery: a focus on academia.Natural product reports · 2021Article
- Bioinformatic and Mechanistic Analysis of the Palmerolide PKS-NRPS Biosynthetic Pathway From the Microbiome of an Antarctic Ascidian.Frontiers in chemistry · 2021Article
- Genome Analysis of a Verrucomicrobial Endosymbiont With a Tiny Genome Discovered in an Antarctic Lake.Frontiers in microbiology · 2021Article
- Comparative Genomics Underlines Multiple Roles of Profftella, an Obligate Symbiont of Psyllids: Providing Toxins, Vitamins, and Carotenoids.Genome biology and evolution · 2020Article
- Highlights of marine natural products having parallel scaffolds found from marine-derived bacteria, sponges, and tunicates.The Journal of antibiotics · 2020Review
- Role of symbiosis in the discovery of novel antibiotics.The Journal of antibiotics · 2020Review
- Uncovering the Core Microbiome and Distribution of Palmerolide inMarine drugs · 2020Article
- Genome Mining of Oxidation Modules in trans-Acyltransferase Polyketide Synthases Reveals a Culturable Source for Lobatamides.Angewandte Chemie (International ed. in English) · 2020Article
- A multiproducer microbiome generates chemical diversity in the marine spongeProceedings of the National Academy of Sciences of the United States of America · 2020Article
- Metagenomic Exploration of the Marine SpongemBio · 2020Article
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A symbiotic lifestyle frequently results in genome reduction in bacteria; the isolation of small populations promotes genetic drift and the fixation of deletions and deleterious mutations over time. Transitions in lifestyle, including host restriction or adaptation to an intracellular habitat, are thought to precipitate a wave of sequence degradation events and consequent proliferation of pseudogenes. We describe here a verrucomicrobial symbiont of the tunicate
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.