Evidence map›Paper›PMID 29181426›Full record

ArticleNeurophotonics2017

Mitochondrial matrix pH as a decisive factor in neurometabolic imaging.

Patrick M Schaefer, Diana Hilpert, Moritz Niederschweiberer, Larissa Neuhauser, Sviatlana Kalinina, Enrico Calzia, Angelika Rueck, Bjoern von Einem, Christine A F von Arnim

Open access · hybridAbstract read
In one paragraph

Article in Neurophotonics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Label-Free Optical Metabolic Imaging in Cells and Tissues.Annual review of biomedical engineering · 2023
    Review
  10. Review
  11. Article
  12. Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Article
  15. Fluorescence lifetime imaging of NAD(P)H upon oxidative stress inFrontiers in bioengineering and biotechnology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Patrick M SchaeferUlm University, Department of Neurology, Ulm, Germany.
Diana HilpertUlm University, Department of Neurology, Ulm, Germany.
Moritz NiederschweibererUlm University, Department of Neurology, Ulm, Germany.
Larissa NeuhauserUlm University, Department of Neurology, Ulm, Germany.
Sviatlana KalininaUlm University, Core Facility Confocal and Multiphoton Microscopy, Ulm, Germany.
Enrico CalziaUniversity Medical School, Institute of Anesthesiological Pathophysiology and Process Engineering, Ulm, Germany.
Angelika RueckUlm University, Core Facility Confocal and Multiphoton Microscopy, Ulm, Germany.
Bjoern von EinemUlm University, Department of Neurology, Ulm, Germany.
Christine A F von ArnimUlm University, Department of Neurology, Ulm, Germany.
Universität Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alterations of cellular bioenergetics are a common feature in most neurodegenerative disorders. However, there is a selective vulnerability of different brain regions, cell types, and even mitochondrial populations to these metabolic disturbances. Thus, the aim of our study was to establish and validate an

Indexed as

energy metabolismmatrix pHmitochondriaNAD(P)H-FLIMredox staterespirometry

Identifiers

PMID29181426
PMCPMC5685807
OpenAlexW2770943031

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.