ReviewBioMed research international2017
Cucurbitaceae Seed Protein Hydrolysates as a Potential Source of Bioactive Peptides with Functional Properties.
Review in BioMed research international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 54 citations in OpenAlex.
- Unlocking the nutritional and economic potential of cucurbitaceae seeds: a comprehensive review of their chemical composition, bioactive compounds, uses and global significance.Food chemistry: X · 2026Review
- Bioactive Peptides From theFood science & nutrition · 2026Review
- Effect of Extraction Methods and Preheat Treatments on the Functional Properties of Pumpkin Seed Protein Concentrate.ACS food science & technology · 2025Article
- Preliminary Data of the Nutritive, Antioxidative, and Functional Properties of Watermelon (Molecules (Basel, Switzerland) · 2025Article
- Protein identification and potential bioactive peptides from pumpkin (Food science & nutrition · 2024Article
- Recent Trends in the Application of Oilseed-Derived Protein Hydrolysates as Functional Foods.Foods (Basel, Switzerland) · 2023Review
- Chayote (Foods (Basel, Switzerland) · 2023Article
- Nutritional, bioactive components and health properties of the milpa triad system seeds (corn, common bean and pumpkin).Frontiers in nutrition · 2023Review
- Dietary phytochemical and metabolic disease prevention: Focus on plant proteins.Frontiers in nutrition · 2023Review
- Protein Hydrolysates Derived from Animals and Plants-A Review of Production Methods and Antioxidant Activity.Foods (Basel, Switzerland) · 2022Review
- Physiological and Clinical Aspects of Bioactive Peptides from Marine Animals.Antioxidants (Basel, Switzerland) · 2022Review
- Comparative assessment ofFrontiers in nutrition · 2022Article
- Effect of Acetylation on Physicochemical and Functional Properties of Commercial Pumpkin Protein Concentrate.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Seeds from Cucurbitaceae plants (squashes, pumpkins, melons, etc.) have been used both as protein-rich food ingredients and nutraceutical agents by many indigenous cultures for millennia. However, relatively little is known about the bioactive components (e.g., peptides) of the Cucurbitaceae seed proteins (CSP) and their specific effects on human health. Therefore, this paper aims to provide a comprehensive review of latest research on bioactive and functional properties of CSP isolates and hydrolysates. Enzymatic hydrolysis can introduce a series of changes to the CSP structure and improve its bioactive and functional properties, including the enhanced protein solubility over a wide range of pH values. Small-sized peptides in CSP hydrolysates seem to enhance their bioactive properties but adversely affect their functional properties. Therefore, medium degrees of hydrolysis seem to benefit the overall improvement of bioactive and functional properties of CSP hydrolysates. Among the reported bioactive properties of CSP isolates and hydrolysates, their antioxidant, antihypertensive, and antihyperglycaemic activities stand out. Therefore, they could potentially substitute synthetic antioxidants and drugs which might have adverse secondary effects on human health. CSP isolates and hydrolysates could also be implemented as functional food ingredients, thanks to their favorable amino acid composition and good emulsifying and foaming properties.
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Registered trials
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