Evidence map›Paper›PMID 29181364›Full record

ArticleJournal of the West African College of Surgeons

MANAGEMENT OF PROSTATE CANCER IN ACCRA, GHANA.

E D Yeboah, A W Hsing, S Mante, J E Mensah, M Y Kyei, J Yarney, V Vanderpuye, K Beecham, Y Tettey, R B Biritwum and 11 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the West African College of Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
0.8field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Incidence and mortality of cancer in the Volta Region of Ghana.Experimental biology and medicine (Maywood, N.J.) · 2020
    Article
  12. Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 1 institution in 1 country.

E D YeboahUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
A W HsingStanford University - Stanford Cancer Institute, CA, USA.
S Mante37 Military Hospital, Accra, Ghana.
J E MensahUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
M Y KyeiUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
J YarneyUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
V VanderpuyeUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
K BeechamUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
Y TetteyUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
R B BiritwumUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
A A AdjeiUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
R GyasiUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
K AsanteUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
K N AmpaduUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
G O KlufioUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
S Gepi-AtteeUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
C OwooUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
D KwamiUniversity of Ghana Medical School(UGMS), Korle Bu Teaching Hospital(KBTH), Accra, Ghana now University of Ghana School of Medicine and Dentistry(UGSMD), Accra, Ghana.
AhiakuVisiting Surgeon from UK.
R PandraVisiting Surgeon, Indian Forces Hospital.
M B CookDivision of Cancer Epidemiology and Genetics, National Cancer Institute(NCI),National Institute of Health(NIH), Bethesda, Maryland, USA.
37 Military Hospital · GH

Funding

Prostate Cancer StudiesZIACP010180 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI ALBANES, DEMETRIUS · 2009 to 2025
$9.9M
6 · The paper itself

Abstract

introductionAfricans living with prostate cancer in Africa face problems of early diagnosis and appropriate treatment.

aimTo study the clinical incidence of prostate cancer, risk factors, TNM stage, their management and outcomes.

methodsA prospective study of Prostate Cancer cases managed at Korle Bu Teaching Hospital and hospitals in Accra, diagnosed by history, abnormal PSA/DRE, physical examination and histologically confirmed by biopsy from 2004 to 2013 was carried out. The cases were TNM staged and managed by approved protocol.

resultsThere were 669 cases with a mean age 70±0.045SE years, median Gleason Score of 7, organ confined Prostate Cancer(PC) in 415(62%), locally advanced in 167(25%) and metastatic Prostate Cancer in 87(13%) cases. The cases were followed for median of 10 months to ≥ 84 months. Organ confined cases were managed by: Radical Prostatectomy (RP) 92 (13.8%) with a mortality of 0.3%; brachytherapy 70 (10.5%) with a mortality of 0.1% and External Beam Radiotherapy (EBRT) 155 (23%) with a mortality 0.7%. In all, 98 men constituting (14.1%) cases with a mean age of 75+0.25SE years, life expectancy <10 years were treated by hormonal therapy with a mortality of 1.7%. Twenty cases who were for active surveillance (GS6), PSA <10ng/ml, life expectancy <10 years later all opted for EBRT. Locally advanced cases 25% all had neoadjuvant hormonal therapy then Brachytherapy in 3 (0.4%) mortality 0.15% and EBRT in 64 (9.5%), mortality 0.59%. Hormonal therapy was given in 100 (15%) locally advanced cases, mortality 5%. Metastatic prostate cancer cases (13%) were managed by hormonal therapy, mortality 6%.

conclusionImproved facilities and dedicated skilled teams led to a significant rise in proportion of organ confined Prostate Cancer from 15.3% to 62% curable by Radical Prostatectomy, brachytherapy or EBRT with longer disease free survival.

Indexed as

Gleason scoreHormonal therapyManagementProstate cancerRadiation therapyRadical prostatectomyStage

Identifiers

PMID29181364
PMCPMC5667721
OpenAlexW3024214884

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.