Evidence map›Paper›PMID 29181102›Full record

ArticleOncology letters2017

MicroRNA-1271 inhibits cellular proliferation of hepatocellular carcinoma.

Andong Qin, Jiehua Zhu, Xingxiang Liu, Dongxiao Zeng, Maolin Gu, Chun Lv

Open access · diamondAbstract read
In one paragraph

Article in Oncology letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Andong QinInstitute of Liver Disease, The Fourth Hospital of Huai'an, Huaian, Jiangsu 223002, P.R. China.
Jiehua ZhuDepartment of Laboratory Medicine, The Affiliated Hospital of Zunyi Medical College, Zunyi, Guizhou 563000, P.R. China.
Xingxiang LiuInstitute of Liver Disease, The Fourth Hospital of Huai'an, Huaian, Jiangsu 223002, P.R. China.
Dongxiao ZengInstitute of Liver Disease, The Fourth Hospital of Huai'an, Huaian, Jiangsu 223002, P.R. China.
Maolin GuInstitute of Liver Disease, The Fourth Hospital of Huai'an, Huaian, Jiangsu 223002, P.R. China.
Chun LvInstitute of Liver Disease, The Fourth Hospital of Huai'an, Huaian, Jiangsu 223002, P.R. China.
Huai'an City Fourth People's Hospital · CNAffiliated Hospital of Zunyi Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-associated mortality worldwide, particularly in China. MicroRNAs (miRs) serve important roles in the pathogenesis of HCC. The present study investigated the function of miR-1271 in HCC. The miR-1271 levels were analyzed by quantitative reverse transcription polymerase chain reaction. Cells growth was examined by MTT assay. Bioinformatics algorithms from TargetScanHuman were used to predict the target genes of miR-1271. The protein level was assayed by western blotting. miR-1271 demonstrated a lower expression level in HCC tissues. Upregulation of miR-1271 suppressed the growth of HepG-2 and Huh-7 cells and induced apoptosis of cells. Forkhead box Q1 (

Indexed as

cell growthhepatocellular carcinomamicroRNA-1271survival

Identifiers

PMID29181102
PMCPMC5696716
OpenAlexW2759578320

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.