Evidence map›Paper›PMID 29181065›Full record

ArticleArchives of medical science : AMS2017

Down-regulation of microRNA-182 and microRNA-183 predicts progression of osteosarcoma.

Mohammad Reza Golbakhsh, Bahram Boddouhi, Negin Hatami, Peyman Karimi Goudarzi, Mohammadreza Shakeri, Emad Yahaghi, Afshin Taheriazam

Open access · goldAbstract read
In one paragraph

Article in Archives of medical science : AMS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Mohammad Reza GolbakhshDepartment of Orthopedics, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Bahram BoddouhiDepartment of Orthopedic Surgery, Rasoul-e-Akram Hospital, Iran University of Medical Science, Tehran, Iran.
Negin HatamiZanjan University of Medical Science, Zanjan, Iran.
Peyman Karimi GoudarziDepartment of Neurosurgery, AJA University of Medical Sciences, Tehran, Iran.
Mohammadreza ShakeriDepartment of Orthopaedic and Trauma Surgery, Shahroud University of Medical Sciences, Shahroud, Iran.
Emad YahaghiDepartment of Molecular Biology, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Afshin TaheriazamDepartment of Orthopedic Surgery, Tehran Medical Sciences Branch, Islamic Azad University, Tehran, Iran.
Aja University of Medical Sciences · IRBaqiyatallah University of Medical Sciences · IRIslamic Azad University Medical Branch of Tehran · IRRasool Akram Hospital · IRShahroud University of Medical Sciences · IRSina Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe aim of this study was to investigate the expression levels of microRNA-182 and microRNA-183 and their association with clinicopathological features in patients with osteosarcoma. MATERIAL AND

methodsTotal RNA was purified from samples and noncancerous bone tissues and then quantitative real-time polymerase chain reaction was applied to evaluate the expression levels of microRNAs, and their relationship with clinicopathological features and survival in osteosarcoma patients.

resultsOur findings showed that expression of MiR-182 was clearly lower in osteosarcoma bone tissue (mean ± SD: 2.84 ±.07) compared with noncancerous bone tissues (6.23 ±1.72,

conclusionsThese findings suggest that MiR-182 and MiR-183 may be associated with progression and metastasis of osteosarcoma.

Indexed as

expressionmarkeroncologypathologytumor

Identifiers

PMID29181065
PMCPMC5701680
OpenAlexW2486404239

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.