ArticleArchives of medical science : AMS2017
Tissue expression of β-catenin and E- and N-cadherins in chronic hepatitis C and hepatocellular carcinoma.
Article in Archives of medical science : AMS, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Frankincense myrrh attenuates hepatocellular carcinoma by regulating tumor blood vessel development through multiple epidermal growth factor receptor-mediated signaling pathways.World journal of gastrointestinal oncology · 2022Article
- The association between micro-RNA gene polymorphisms and the development of hepatocellular carcinoma in Egyptian patients.Archives of medical science : AMS · 2022Article
- Quantitative Expression of Key Cancer Markers in the AS-30D Hepatocarcinoma Model.Frontiers in oncology · 2021Article
- Comprehensive analysis of key lncRNAs in HCV-positive hepatocellular carcinoma.Archives of medical science : AMS · 2021Article
- Effects of free and nanoparticulate curcumin on chemically induced liver carcinoma in an animal model.Archives of medical science : AMS · 2021Article
- Differential expression of angiogenesis-related miRNAs andArchives of medical science : AMS · 2020Article
- Perinatal transmission of hepatitis C virus: an update.Archives of medical science : AMS · 2020Article
- Epithelial Mesenchymal and Endothelial Mesenchymal Transitions in Hepatocellular Carcinoma: A Review.BioMed research international · 2019Review
- 5-Hydroxy-4'-Nitro-7-Propionyloxy-Genistein Inhibited Invasion and Metastasis via Inactivating Wnt/b-Catenin Signal Pathway in Human Endometrial Carcinoma Ji Endometrial Cells.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
introductionThe role of Wnt/ β -catenin signaling pathway in HCV-associated hepatocellular carcinogenesis is still unknown. MATERIAL AND
methodsThis study aimed to perform quantitative analysis of immuno- and hybridocytochemical expression of β -catenin, E- and N-cadherins and HCV proteins (C, NS3, NS5A) in long-lasting (≥ 20 years) chronic hepatitis C (CH-C) (
resultsTypical membranous expression of β -catenin in the control liver was higher than in the CH-C and HCC (
conclusionsAlterations in cellular locations of β -catenin and E-cadherin in CH-C and HCC pointed to structural disturbances in intercellular junctions in the livers and presence of the transcriptionally inactive form of β -catenin. The reduced expression of E-cadherin in long-lasting CH-C may represent an early indicator of the epithelial-mesenchymal transition. The most important role in modulation of the Wnt/ β -catenin pathway
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