Evidence map›Paper›PMID 29180876›Full record

ArticleOncoTargets and therapy2017

The effect of

Junjun Lu, He Li, Peng Guo, Rui Shen, Yingbin Luo, Qiao Ge, Wenfei Shi, Yan Li, Weikang Zhu

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05501158 (CYP2D6 Genotypes and Breast Cancer Clinical Outcomes in the Indonesian Population), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05501158 naunknown statusnot on this mapstarted 2021, after this paper: background citation

CYP2D6 Genotypes and Breast Cancer Clinical Outcomes in the Indonesian Population (Pengaruh Genotipe CYP2D6 Terhadap Efektivitas Penggunaan Tamoksifen Untuk Pasien Kanker Payudara ER+ Pada Populasi Indonesia)

TypeinterventionalSponsorNalagenetics Pte LtdRan2021 to 2024Enrolled150ConditionsBreast CancerArmsTamoxifen
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Pharmacogenomics of breast cancer: highlighting CYP2D6 and tamoxifen.Journal of cancer research and clinical oncology · 2020
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Junjun Lu *Department of Tumor, Shanghai Municipal Hospital of Traditional Chinese Medicine.
He Li *Department of Traditional Chinese Medicine, Shanghai Jiao Tong University Medical School Affiliated Ruijin Hospital.
Peng GuoDepartment of Tumor, Shanghai Municipal Hospital of Traditional Chinese Medicine.
Rui ShenDepartment of Function, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai.
Yingbin LuoDepartment of Tumor, Shanghai Municipal Hospital of Traditional Chinese Medicine.
Qiao GeDepartment of Tumor, Ninghai Hospital of Traditional Chinese Medicine, Ningbo, Zhejiang, China.
Wenfei ShiDepartment of Tumor, Shanghai Municipal Hospital of Traditional Chinese Medicine.
Yan LiDepartment of Tumor, Shanghai Municipal Hospital of Traditional Chinese Medicine.
Weikang ZhuDepartment of Tumor, Shanghai Municipal Hospital of Traditional Chinese Medicine.
Shanghai Traditional Chinese Medicine Hospital · CNRuijin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the effect of

methodsMeta-analysis of retrospective cohort studies published in July 2017 was performed. Fifteen studies with 1,794 Asian breast cancer patients were included, using strict eligibility requirements. Associations of disease-free survival (DFS), overall survival (OS) and recurrence rate after tamoxifen intake, with

results

conclusionIn conclusion, our meta-analysis suggests that significant association of

Indexed as

Asiabreast cancerCYP2D6 *10polymorphismtamoxifen adjuvant treatment

Identifiers

PMID29180876
PMCPMC5692201
OpenAlexW2769256842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.