Evidence map›Paper›PMID 29180592›Full record

Trial reportBMJ open2017

Cost-effectiveness of a preferred intensity exercise programme for young people with depression compared with treatment as usual: an economic evaluation alongside a clinical trial in the UK.

David Turner, Tim Carter, Tracey Sach, Boliang Guo, Patrick Callaghan

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01474837 (The H.E.A.L.T.H. Project), which is not on this map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01474837 nacompletednot on this map

The H.E.A.L.T.H. Project: Help Enabling Active Lifestyles Toward Health in Young People With Depression.

TypeinterventionalSponsorUniversity of NottinghamRan2011Enrolled86ConditionsDepressionArmsIntervention: Exercise and motivational interviewing
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

David TurnerNorwich Medical School, University of East Anglia, Norwich, UK.
Tim CarterSchool of Health Sciences, University of Nottingham, Nottingham, UK.
Tracey SachNorwich Medical School, University of East Anglia, Norwich, UK.
Boliang GuoDivision of Psychiatry and Applied Psychology, University of Nottingham, Nottingham, UK.
Patrick CallaghanSchool of Health Sciences, University of Nottingham, Nottingham, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the cost-effectiveness of preferred intensity exercise programme for young people with depression compared with a treatment as usual control group.

designA 'within trial' cost-effectiveness and cost-utility analysis conducted alongside a randomised controlled trial. The perspective of the analysis was the UK National Health Service and social services.

settingThe intervention was provided in a community leisure centre setting.

participants86 young people aged 14-17 years attending Tier 2 and Tier 3 CAMHS (Child and Adolescent Mental Health Services) outpatient services presenting with depression.

interventionsThe intervention comprised 12 separate sessions of circuit training over a 6-week period. Sessions were supervised by a qualified exercise therapist. Participants also received treatment as usual. The comparator group received treatment as usual.

resultsWe found improvements in the Children's Depression Inventory-2 (CDI-2) and estimated cost-effectiveness at £61 per point improvement in CDI-2 for the exercise group compared with control. We found no evidence that the exercise intervention led to differences in quality-adjusted life years (QALY). QALYs were estimated using the EQ-5D-5L (5-level version of EuroQol-5 dimension).

conclusionsThere is evidence that exercise can be an effective intervention for adolescents with depression and the current study shows that preferred intensity exercise could also represent a cost-effective intervention in terms of the CDI-2. TRIAL REGISTRATION NUMBER: NCT01474837.

Indexed as

AdolescentCost-Benefit AnalysisDepressionExercise TherapyFemaleHumansMaleQuality-Adjusted Life YearsQuality of LifeSingle-Blind MethodUnited KingdomHealth Economics

Identifiers

PMID29180592
PMCPMC5719311

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.