Evidence map›Paper›PMID 29180537›Full record

ArticleSexually transmitted infections2018

A cross-sectional study examining associations between substance use frequency, problematic use and STIs among youth living with HIV.

Kristi E Gamarel, Sharon Nichols, Christopher W Kahler, Andrew O Westfall, Michelle A Lally, Craig M Wilson, Adolescent Medicine Trials Network for HIV/AIDS Intervention

Abstract readMulticenter Study
In one paragraph

Article in Sexually transmitted infections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
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  6. Transmission Risk Among Youth Living With HIV in the U.S.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kristi E GamarelDepartment of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, Michigan, USA.ORCID 0000-0001-9405-7515
Sharon NicholsDepartment of Neuroscience, University of California, San Diego, San Diego, CA, USA.
Christopher W KahlerCenter for Alcohol & Addiction Studies and Department of Behavioral and Social Science, Brown University School of Public Health, Providence, Rhode Island, USA.
Andrew O WestfallDepartment of Medicine, University of Alabama at Birmingham USA, Birmingham, Alabama, USA.
Michelle A LallyLifespan Hospital System, Providence, Rhode Island, USA.
Craig M WilsonDepartment of Epidemiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Adolescent Medicine Trials Network for HIV/AIDS Intervention
University of Alabama at Birmingham · USBrown University · USMichigan Department of Health and Human Services · USProvidence College · USUniversity of California San Diego · US

Funding

Adol. Medicine Trials Network for HIV/AIDS InterventionsU01HD040474 · NICHD · WESTAT, INC. · PI HARRIS, DONALD ROBERT · 2001 to 2016
$114.4M
LEADERSHIP GROUP FOR ADOLESCENT MEDICINE TRIALS NETWORKU01HD040533 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WILSON, CRAIG M · 2001 to 2016
$76.4M
Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI CURT G BECKWITH, DEBBIE M. CHENG · 1998 to 2026
$51.7M
Scientific/Technical CoreP2CHD041028 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Sarah A. Burgard · 2017 to 2026
$6.5M
Minority Populations Resource CoreU24AA022000 · NIAAA · BROWN UNIVERSITY · PI OPERARIO, DON · 2012 to 2015
$1.9M
NIAAA NIH HHS U24 AA022000NIAID NIH HHS P30 AI042853NICHD NIH HHS P2C HD041028NICHD NIH HHS U01 HD040474NICHD NIH HHS U01 HD040533NIDA NIH HHS L30 DA040191
6 · The paper itself

Abstract

objectivesThis study sought to examine the prevalence of STIs and whether substance use frequency and/or problematic use-specifically alcohol, marijuana and other drugs-was associated with having an STI diagnosis among youth living with HIV (YLWH)

methodsA sample of 823 YLWH were recruited at 14 adolescent HIV clinics through the Adolescent Medicine Trials Network for HIV Interventions. Study staff abstracted STI data from medical records for up to 26 weeks prior to participants' completing a cross-sectional survey including the ASSIST (Alcohol, Smoking and Substance Involvement Screening Test), which measures substance use frequency and consequences.

resultsAlmost one-third of youth had been diagnosed with an STI (30.5%) at the time of their baseline assessment. In multivariable analyses, those who engaged in weekly or greater marijuana use (adjusted OR (AOR)=10.66, 95% CI: 4.39 to 25.87, P<0.001) had an increased odds of being diagnosed with an STI. Additionally, youth who met alcohol use criteria for moderate (AOR=5.23, 95% CI: 2.50 to 10.93, P<0.001) and high risk (AOR=6.53, 95% CI: 1.20 to 35.68, P<0.05) alcohol use had an increased odds of being diagnosed with an STI compared with low-risk alcohol users.

conclusionsStudy findings underscore the need to investigate the role of greater frequency of marijuana use and problematic alcohol use in STI incidence among YLWH. Given the associations between both substance use frequency and problematic use in STI diagnoses among YLWH seen in HIV care settings, clinicians should use validated substance use screening tools which capture both frequencies and consequences in order to identify YLWH who may need further evaluation and treatment.

Indexed as

AdolescentAlcohol DrinkingCross-Sectional StudiesFemaleHIV InfectionsHumansMaleMarijuana AbusePrevalenceSex DistributionSexually Transmitted DiseasesSubstance-Related DisordersTransgender PersonsUnited StatesYoung AdultadolescentHIVsubstance misuse

Identifiers

PMID29180537
PMCPMC6002747
OpenAlexW2768404199

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.