Evidence map›Paper›PMID 29180482›Full record

ArticlePhysiological reports2017

Deep-targeted sequencing of endothelial nitric oxide synthase gene exons uncovers exercise intensity and ethnicity-dependent associations with post-exercise hypotension.

Linda S Pescatello, Elizabeth D Schifano, Garrett I Ash, Gregory A Panza, Lauren M L Corso, Ming-Hui Chen, Ved Deshpande, Amanda Zaleski, Burak Cilhoroz, Paulo Farinatti and 3 more

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Linda S PescatelloDepartment of Kinesiology, University of Connecticut, Storrs, Connecticut Linda.Pescatello@uconn.edu.
Elizabeth D SchifanoDepartment of Statistics, University of Connecticut, Storrs, Connecticut.
Garrett I AshSchool of Nursing, Yale University, New Haven, Connecticut.ORCID http://orcid.org/0000-0002-8655-7525
Gregory A PanzaDepartment of Kinesiology, University of Connecticut, Storrs, Connecticut.
Lauren M L CorsoDepartment of Kinesiology, University of Connecticut, Storrs, Connecticut.
Ming-Hui ChenDepartment of Statistics, University of Connecticut, Storrs, Connecticut.
Ved DeshpandeDepartment of Statistics, University of Connecticut, Storrs, Connecticut.
Amanda ZaleskiDepartment of Kinesiology, University of Connecticut, Storrs, Connecticut.
Burak CilhorozDepartment of Kinesiology, University of Connecticut, Storrs, Connecticut.
Paulo FarinattiDepartment of Physical Activity Sciences, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Beth A TaylorDepartment of Kinesiology, University of Connecticut, Storrs, Connecticut.
Rachel J O'NeillInstitute for Systems Genomics, University of Connecticut, Storrs, Connecticut.
Paul D ThompsonDepartment of Preventive Cardiology, Hartford Hospital, Hartford, Connecticut.
University of Connecticut · USHartford Hospital · USUniversidade do Estado do Rio de Janeiro · BRYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Multidisciplinary Behavioral Research Training in T1DT32DK097718 · NIDDK · YALE UNIVERSITY · PI GREY, MARGARET, WEINZIMER, STUART ALAN · 2012 to 2017
$771k
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS T32 DK097718
6 · The paper itself

Abstract

In previous studies, we found an endothelial nitric oxide synthase gene (

Indexed as

ExercisePolymorphism, Single NucleotideAdolescentAdultBlack or African AmericanBlood PressureExonsFemaleHumansMaleMiddle AgedNitric Oxide Synthase Type IIIPost-Exercise HypotensionWhite PeopleNitric Oxide Synthase Type IIINOS3 protein, humanBlood PressureExerciseHypertensionPolymorphism

Identifiers

PMID29180482
PMCPMC5704084
OpenAlexW2769092158

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.