Evidence map›Paper›PMID 29180447›Full record

ArticleThe Journal of biological chemistry2018

A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell.

Akira Hashiramoto, Yoshitake Konishi, Koichi Murayama, Hiroki Kawasaki, Kohsuke Yoshida, Ken Tsumiyama, Kimie Tanaka, Masaru Mizuhara, Toshio Shiotsuki, Hitomi Kitamura and 5 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. An 11-bp Indel Polymorphism within theAnimals : an open access journal from MDPI · 2019
    Article
  7. T Cells and Regulated Cell Death: Kill or Be Killed.International review of cell and molecular biology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Akira HashiramotoFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Yoshitake KonishiFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Koichi MurayamaFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Hiroki KawasakiFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Kohsuke YoshidaFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Ken Tsumiyamathe Department of Medicine, Rheumatic Diseases Unit, Kyushu University Beppu Hospital, Beppu 874-0838.
Kimie TanakaFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Masaru MizuharaFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Toshio ShiotsukiFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Hitomi KitamuraFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Koichiro KomaiFrom the Department of Biophysics, Kobe University Graduate School of Health Science, Kobe 654-0142.
Tomoatsu Kimurathe Department of Orthopedic Surgery, Faculty of Medicine, University of Toyama, 3190 Gofuku, 930-0194 Toyama.
Hideo Yagitathe Department of Immunology, Juntendo University School of Medicine, Tokyo 113-8431, and.
Kazuko Shiozawathe Department of Rheumatology, Hyogo Prefectural Kakogawa Medical Center, Kakogawa 675-8555, Japan.
Shunichi Shiozawathe Department of Medicine, Rheumatic Diseases Unit, Kyushu University Beppu Hospital, Beppu 874-0838, shiozawa@port.kobe-u.ac.jp.
Kobe University · JPKyushu University Beppu Hospital · JPEdogawa Hospital · JPJuntendo University · JPUniversity of Toyama · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) is a chronic polyarthritis of unknown etiology. To unravel the molecular mechanisms in RA, we performed targeted DNA sequencing analysis of patients with RA. This analysis identified a variant of the

Indexed as

ApoptosisAnimalsArthritis, RheumatoidExonsHumansIntronsMiceMice, Inbred C57BLMice, TransgenicPolymorphism, Single NucleotideProtein DomainsReceptors, Tumor Necrosis Factor, Member 25Signal TransductionT-LymphocytesTumor Necrosis Factor Ligand Superfamily Member 15Receptors, Tumor Necrosis Factor, Member 25TNFRSF25 protein, humanTnfsf15 protein, mouseTumor Necrosis Factor Ligand Superfamily Member 15apoptosisarthritiscaspasedeath domainlymphocyte

Identifiers

PMID29180447
PMCPMC5808757
OpenAlexW2770459408

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.