ArticleJMIR research protocols2017
Behavioral Interventions to Prevent or Delay Dementia: Protocol for a Randomized Comparative Effectiveness Study.
Article in JMIR research protocols, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02265757 (Comparative Effectiveness of Behavioral Interventions to Prevent or Delay Dementia), which is not on this map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Comparative Effectiveness of Behavioral Interventions to Prevent or Delay Dementia (CEBIPODD)
Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Multimodal cognitive and behavioral interventions for patients with MCI: a systematic review and meta-analysis on cognition and mood.Frontiers in aging neuroscience · 2024Pooled it
- Psychotherapeutic interventions in individuals at risk for Alzheimer's dementia: a systematic review.Alzheimer's research & therapy · 2022Pooled it
- Recruitment of a multi-site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021Trial
- Comparative Effectiveness of Behavioral Interventions on Quality of Life for Older Adults With Mild Cognitive Impairment: A Randomized Clinical Trial.JAMA network open · 2019Trial
- Behavioral Interventions in Mild Cognitive Impairment (MCI): Lessons from a Multicomponent Program.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2022Review
- Comparative Effects of Physical Exercise and Other Behavioral Interventions on Functional Status Outcomes in Mild Cognitive Impairment.Journal of the International Neuropsychological Society : JINS · 2021Article
- Truly Cross-fit: The Association of Exercise and Clinical Outcomes: Introduction to a JINS Special Section.Journal of the International Neuropsychological Society : JINS · 2021Review
- Computerized Cognitive Training (CCT) versus Yoga Impact on 12 Month Post Intervention Cognitive Outcome in Individuals with Mild Cognitive Impairment.Brain sciences · 2021Article
- Psychometric properties of the self-efficacy for managing mild cognitive impairment scale.International journal of geriatric psychiatry · 2021Article
- Memory Support System training in mild cognitive impairment: Predictors of learning and adherence.Neuropsychological rehabilitation · 2021Article
- Functional ability is associated with higher adherence to behavioral interventions in mild cognitive impairment.The Clinical neuropsychologist · 2020Article
- A Survey of Patient and Partner Outcome and Treatment Preferences in Mild Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2018Article
- Health concerns and attitudes towards research participation in a community of rural Black Americans.Clinical gerontologistArticle
- Effects of care partner type on outcomes from a multicomponent behavioral intervention for mild cognitive impairment.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
28 authors.
Funding
Abstract
backgroundCurrently, people at risk for dementia and their caregivers are confronted with confusing choices about what behavioral interventions are most effective.
objectiveThe objective of this study is to determine which empirically supported behavioral interventions most impact the outcomes highly valued by patients with mild cognitive impairment and their partners.
methodsThis protocol describes a comparative effectiveness trial targeting 300 participants with mild cognitive impairment and their study partners. The trial is being conducted at the Mayo Clinic campuses in Arizona, Florida, Minnesota, and the University of Washington in Seattle. The study examines the contribution of five behavioral interventions (yoga, memory compensation training, computerized cognitive training, support groups, and wellness education) on primary outcomes of participant and partner quality of life and self-efficacy. In this unique 10-day multicomponent intervention, groups of couples were randomized to have one of the five interventions withheld while receiving the other four. Although the longitudinal follow-up is still under way, enrollment results are available and reported.
resultsIn total, 272 couples have been enrolled in the trial and follow-up visits continue. Outcomes will be assessed at the end-of-intervention and 6-, 12-, and 18-month follow-ups. We anticipate reporting on our primary and secondary outcomes across time points in the next 2 years.
conclusionsThis paper describes the protocol for a randomized comparative effectiveness study of behavioral interventions to prevent or delay dementia. We describe of the rationale, design, power analysis, and analysis plan. Also because enrollment is complete and we are in follow-up phases of the study, we have included enrollment data from the trial.
trial registrationClinicalTrials.gov NCT02265757; http://clinicaltrials.gov/ctsshow/ NCT02265757 (Archived by WebCite at http://www.webcitation.org/6ueRfwSYv).
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